Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP10 | P09238 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28560616 | 0.87 | KDM4E (0.36) | GPR119HDAC1PARP1NAMPT | |
| SCHEMBL29455207 | 0.87 | KDM4E (0.36) | GPR119HDAC1PARP1NAMPT | |
| SCHEMBL28553866 | 0.81 | ENPP2 (0.48) | — | |
| SCHEMBL29455203 | 0.81 | ENPP2 (0.48) | — | |
| SCHEMBL29455206 | 0.78 | TACR1 (0.37) | GPR119PARP1NAMPT | |
| SCHEMBL29455204 | 0.74 | KDM4E (0.43) | GPR119USP30NAMPT | |
| SCHEMBL16962692 | 0.74 | ENPP2 (0.43) | GPR119HDAC1 | |
| SCHEMBL16961993 | 0.74 | ENPP2 (0.43) | GPR119HDAC1 | |
| SCHEMBL16961995 | 0.74 | ENPP2 (0.43) | GPR119HDAC1 | |
| SCHEMBL29455221 | 0.71 | EPHX2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778274-B | Nitrogen-containing heterocyclic derivative and preparation thereof | 四川海思科制药有限公司 | 2022-02-15 | — | — | CN | disclosed |