SCHEMBL2945561

SCHEMBL2945561

CCN(CC)CC#C[C](C)C

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 4/20 0.52
CHRM2 P08172 3/20 0.52
CHRM4 P08173 3/20 0.52
CHRM5 P08912 3/20 0.52
CHRM3 P20309 3/20 0.52
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
NPY2R P49146 1/20 0.32
GAA P10253 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.31
KCNH2 Q12809 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9222486 0.77 CHRM2 (0.45) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL10257125 0.76 CHRM2 (0.59) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL6380588 0.75 CHRM1 (0.54) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL135037 0.70 CHRM1 (0.54) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL936173 0.69
SCHEMBL937076 0.69 CHRM2 (0.52) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL136867 0.67
SCHEMBL9029298 0.67 CHRM1 (0.72) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL9029220 0.67 CHRM1 (0.61) CHRM1CHRM2CHRM4CHRM5CHRM3
SCHEMBL1649706 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090208576-A1 Orally Disintegrating Tablets RUBICON RESEARCH PRIVATE LIMITED (IN) 2009-08-20 US claimed
EP-2001450-A2 DIRECTLY COMPRESSIBLE COMPOSITE FOR ORALLY DISINTEGRATING TABLETS Rubicon Research Private Limited (IN) 2008-12-17 EP claimed
WO-2007113856-A2 DIRECTLY COMPRESSIBLE COMPOSITE FOR ORALLY DISINTEGRATING TABLETS RUBICON RESEARCH PRIVATE LIMITED (IN) 2007-10-11 WO claimed
EP-0580860-B1 METHOD OF MANUFACTURING SOLID DISPERSION NIPPON SHINYAKU CO LTD (JP) 1997-10-22 EP claimed
EP-2001450-B1 DIRECTLY COMPRESSIBLE COMPOSITE FOR ORALLY DISINTEGRATING TABLETS RUBICON RES PRIVATE LIMITED (IN) 2019-01-30 EP disclosed
EP-1660050-B1 Ibuprofen-containing fast dissolving tablet WYETH LLC (US) 2016-11-23 EP disclosed
US-20140249190-A1 Fast Dissolving Tablet WYETH LLC (US) 2014-09-04 US disclosed
CN-101460150-B Directly compressible compound for orally disintegrating tablets RUBICON RES PRIVATE LTD 2014-02-12 CN disclosed
US-8580305-B2 Tablet quickly melting in oral cavity NIPPON SHINYAKU CO., LTD. (JP) 2013-11-12 US disclosed
US-20130296385-A1 Fast Dissolving Tablet WYETH LLC (US) 2013-11-07 US disclosed
US-8545890-B2 Orally disintegrating tablets RUBICON RESEARCH PRIVATE LIMITED (IN) 2013-10-01 US disclosed
US-8202538-B2 Orally disintegrating layered compositions CAPRICORN PHARMA, INC. (US) 2012-06-19 US disclosed
US-5498422-A WATER SOLUBLE POLYMERS, CARBOXYVINYL POLYMERS OR SODIUM POLYACRYLATES NIPPON SHINYAKU COMPANY LIMITED (JP) 1996-03-12 US disclosed
US-5456923-A Produced without heating a drug and a polymer to or beyond their melting points and without using an organic solvent NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-10-10 US disclosed
EP-0497977-B1 GASTRIC PREPARATION NIPPON SHINYAKU CO LTD (JP) 1995-03-15 EP disclosed
EP-0627218-A1 FAST SOLUBLE TABLET NIPPON SHINYAKU COMPANY, LIMITED (JP) 1994-12-07 EP disclosed
US-5368861-A Gastric preparation with sustained release NIPPON SHINYAKU CO., LTD. (JP) 1994-11-29 US disclosed
EP-0580861-A1 CAPSULE NIPPON SHINYAKU COMPANY, LIMITED (JP) 1994-02-02 EP disclosed
EP-0580860-A1 METHOD OF MANUFACTURING SOLID DISPERSION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1994-02-02 EP disclosed
EP-0497977-A1 GASTRIC PREPARATION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1992-08-12 EP disclosed