SCHEMBL2945571

SCHEMBL2945571

Nc1[c]ccc(N)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276000 0.79
SCHEMBL8880901 0.75
SCHEMBL8880898 0.75
SCHEMBL8880194 0.75
SCHEMBL934331 0.72
SCHEMBL9833497 0.70 GAA (0.32)
SCHEMBL4895507 0.68
SCHEMBL526351 0.66 ALDH1A1 (0.50)
SCHEMBL20553278 0.65
SCHEMBL5510055 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7758658-B2 Colouring composition KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-07-20 US disclosed
US-20090038087-A1 An aqueous coloring composition for human hair comprising an oxidative dyestuff precursor, a coupling agent and an arylated silicone; combability, elasticity, smoothness and softnessimproves hair with excellent shine, vibrancy and brilliance KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2009-02-12 US disclosed