Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | CCL2 | P13500 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29455885 | 0.92 | BRD4 (0.45) | BRD4ARKCNH2RET | |
| SCHEMBL29455792 | 0.91 | BRD4 (0.45) | BRD4ARKCNH2RET | |
| SCHEMBL29455845 | 0.90 | BRD4 (0.44) | BRD4ARKCNH2RET | |
| SCHEMBL29455895 | 0.88 | BRD4 (0.51) | BRD4RETCCL2 | |
| SCHEMBL29455801 | 0.87 | BRD4 (0.46) | BRD4RETGPR119 | |
| SCHEMBL29455967 | 0.86 | BRD4 (0.48) | BRD4RET | |
| SCHEMBL29455975 | 0.86 | BRD4 (0.43) | BRD4ARKCNH2RETCCL2 | |
| SCHEMBL29455799 | 0.84 | BRD4 (0.49) | BRD4ARKCNH2RETGPR119 | |
| SCHEMBL22137542 | 0.81 | BRD4 (0.52) | BRD4ARKCNH2 | |
| SCHEMBL29455911 | 0.81 | BRD4 (0.52) | BRD4ARKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12636290-B2 | BET inhibitors for modulating DUX4 expression in FSHD | SAINT LOUIS UNIVERSITY (US) | 2026-05-26 | — | — | US | disclosed |
| US-20220079951-A1 | BET INHIBITORS FOR MODULATING DUX4 EXPRESSION IN FSHD | SAINT LOUIS UNIVERSITY (US) | 2022-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220079951-A1 | BET INHIBITORS FOR MODULATING DUX4 EXPRESSION IN FSHD | BRDT, PHKB, BET1 | BRD4 4/4885AR 151/4885KCNH2 4700/4885 |
| US-12636290-B2 | BET inhibitors for modulating DUX4 expression in FSHD | BRDT, BET1, PHKB | BRD4 6/4885AR 58/4885KCNH2 4011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.