Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27211435 | 1.00 | PIK3CD (0.52) | PIK3CDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL27211332 | 0.86 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL25344642 | 0.86 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30473674 | 0.85 | PIK3CD (0.51) | PIK3CDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL25344277 | 0.85 | PIK3CD (0.51) | PIK3CDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL27211356 | 0.85 | PIK3CD (0.51) | PIK3CDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL25343649 | 0.85 | PDE4B (0.47) | PIK3CDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL29457556 | 0.85 | PDE4B (0.47) | PIK3CDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL25343640 | 0.85 | PDE4B (0.47) | PIK3CDMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL25342400 | 0.85 | PDE4B (0.47) | PIK3CDGPR119PRMT5PDE4BHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116390917-A | MRGX2 antagonists | 葛兰素史密斯克莱知识产权发展有限公司 | 2023-07-04 | — | — | CN | disclosed |
| WO-2022073904-A1 | MRGX2 ANTAGONISTS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-04-14 | — | — | WO | disclosed |