Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 11/20 | 0.38 |
| ▸ | FPR2 | P25090 | 5/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29457021 | 0.88 | SCN4A (0.46) | SCN9AFPR2MAPTSCN4ACARM1 | |
| SCHEMBL29457075 | 0.86 | CARM1 (0.42) | SCN9AFPR2ACACACARM1PRMT6 | |
| SCHEMBL29457033 | 0.82 | APLNR (0.34) | SCN9AFPR2 | |
| SCHEMBL29457068 | 0.81 | SCN9A (0.45) | SCN9AFPR2 | |
| SCHEMBL29457101 | 0.81 | LPAR1 (0.39) | SCN9AFPR2 | |
| SCHEMBL29457058 | 0.80 | PTGER4 (0.39) | SCN9AFPR2CARM1PRMT6 | |
| SCHEMBL29457020 | 0.79 | CYP3A4 (0.40) | — | |
| SCHEMBL29457113 | 0.78 | CARM1 (0.42) | CARM1PRMT6 | |
| SCHEMBL29457090 | 0.77 | PARP10 (0.46) | SCN9AACACBPARP10SMN1; SMN2ACACA | |
| SCHEMBL19738832 | 0.76 | CACNA1I (0.46) | PARP10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073904-A1 | MRGX2 ANTAGONISTS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-04-14 | — | — | WO | disclosed |