Itaconate

Itaconate

SCHEMBL2945767

C=C(C)C(=O)O.C=C(CC(=O)O)C(=O)O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.62
HSD17B10 Q99714 1/20 0.62
LDHA P00338 1/20 0.40
SRR Q9GZT4 1/20 0.40
TET2 Q6N021 5/20 0.38
ALDH1A1 P00352 1/20 0.36
TET3 O43151 1/20 0.36
TET1 Q8NFU7 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
GRIK1 P39086 1/20 0.34
GRIK2 Q13002 1/20 0.34
GRM1 Q13255 1/20 0.34
GRM2 Q14416 1/20 0.34
TGFBR1 P36897 1/20 0.34
KDM4E B2RXH2 2/20 0.32
TSHR P16473 1/20 0.32
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PHF8 Q9UPP1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Itaconate SCHEMBL5429101 1.00 ALOX15 (0.62) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL31425252 1.00 ALOX15 (0.62) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL9068843 0.93 ALOX15 (0.56) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL3025025 0.93 ALOX15 (0.56) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL2564169 0.92 ALOX15 (0.65) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL8659131 0.91 ALOX15 (0.54) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL5447650 0.89 ALOX15 (0.68) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL8429819 0.89 ALOX15 (0.83) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL28072800 0.89 ALOX15 (0.63) ALOX15HSD17B10LDHASRRTET2
Itaconate SCHEMBL21523 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4361183-A1 HIGH MOLECULAR WEIGHT ANIONIC POLYACRYLAMIDES SNF Group (FR) 2024-05-01 EP claimed
US-20240132711-A1 HIGH MOLECULAR WEIGHT ANIONIC POLYACRYLAMIDES SNF GROUP (FR) 2024-04-25 US claimed
CN-105060759-A Preparation method of slow-release polycarboxylate superplasticizer CNBM ZHONGYAN TECHNOLOGY CO LTD 2015-11-18 CN claimed
CN-104357957-A Preparation method of carbon fiber precursor WEIHAI TUOZHAN FIBER CO LTD 2015-02-18 CN claimed
US-6077602-A POLYOLEFIN COATED WITH AN ACRYLIC POLYMER MOBIL OIL CORPORATION (US) 2000-06-20 US claimed
EP-0828608-A4 HEAT SEALABLE FILM MOBIL OIL CORP (US) 1998-06-10 EP claimed
EP-0828608-A1 HEAT SEALABLE FILM MOBIL OIL CORPORATION (US) 1998-03-18 EP claimed
WO-1996038300-A1 HEAT SEALABLE FILM MOBIL OIL CORPORATION (US) 1996-12-05 WO claimed
US-5238678-A Undercoatings consisting of film-forming adhesives an acrylate copolymers with a carboxylic acid and/or vinyl acetate, methyl methacrylate, acrylamide; wear resistance, softness, adhesion POLA CHEMICAL INDUSTRIES, INC. (JP) 1993-08-24 US claimed
US-4463149-A UNSATURATED POLYSILOXANES POLYMER TECHNOLOGY CORPORATION (US) 1984-07-31 US claimed
US-4300886-A Shaped dental articles BAYER AKTIENGESELLSCHAFT (DE) 1981-11-17 US claimed
JP-61227831-A None JP disclosed
CN-117887384-A Negative electrode water-based binder for improving binding performance and preparation method thereof 常棣科技(深圳)有限公司 2024-04-16 CN disclosed
WO-2023211667-A1 MULTILAYER RADIOCHROMIC STRUCTURES AND USES THEREOF ISP INVESTMENTS LLC (US) 2023-11-02 WO disclosed
US-20230265301-A1 INK-JET INK NIPPON SHOKUBAI CO., LTD. (JP) 2023-08-24 US disclosed
EP-0079165-B1 (METH) ACRYLIC ACID/ITACONIC ACID COPOLYMERS, THEIR PREPARATION AND USE AS ANTISCALANTS PFIZER INC. (US) 1985-03-20 EP disclosed
EP-0031701-B1 A PROCESS FOR PRODUCING A LAMINATED MEMBER AND A LAMINATED MEMBER PRODUCED THEREBY TOYO INK MANUFACTURING CO., LTD. (JP) 1984-09-19 EP disclosed
EP-0114258-A1 Resin encapsulation type photo-semiconductor devices KABUSHIKI KAISHA TOSHIBA (JP) 1984-08-01 EP disclosed
EP-0063561-A1 CROSS-LINKED HYDROPHILIC POLYMERS. PATEL PRAVIN GORDHANBHAI (GB) 1982-11-03 EP disclosed
WO-1982001553-A1 CROSS-LINKED HYDROPHILIC POLYMERS PATEL PRAVIN 1982-05-13 WO disclosed