Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29459335 | 0.87 | NPC1 (0.32) | NPC1RAB9A | |
| SCHEMBL29459218 | 0.84 | PNMT (0.30) | NPC1RAB9APNMT | |
| SCHEMBL29459317 | 0.82 | NPC1 (0.32) | NPC1RAB9APNMTALDH1A1 | |
| SCHEMBL29459327 | 0.81 | NPC1 (0.43) | NPC1RAB9APNMTALDH1A1HTR7 | |
| SCHEMBL29459211 | 0.81 | NPC1 (0.41) | NPC1RAB9APNMTALDH1A1HTR7 | |
| SCHEMBL29459161 | 0.74 | NPC1 (0.38) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL29775014 | 0.74 | PNMT (0.37) | NPC1RAB9APNMTALDH1A1HTR7 | |
| SCHEMBL29459239 | 0.73 | NPC1 (0.36) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL29700197 | 0.72 | PNMT (0.36) | NPC1RAB9APNMTHTR7HTR2B | |
| SCHEMBL29907869 | 0.70 | PNMT (0.43) | NPC1RAB9APNMTHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3953403-A1 | CATALYST SYSTEM | Borealis AG (AT) | 2022-02-16 | — | — | EP | disclosed |