SCHEMBL29459507

SCHEMBL29459507

O=C1c2ccccc2C(=O)N1CCCN1CCC(F)CC1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 5/20 0.62
MAOB P27338 2/20 0.61
HTR7 P34969 1/20 0.60
HRH1 P35367 1/20 0.60
DRD3 P35462 1/20 0.60
HTR2B P41595 1/20 0.60
ALDH1A1 P00352 1/20 0.58
DRD2 P14416 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28713961 0.91 HTR1A (0.65) HTR1AMAOBHTR7HRH1DRD3
SCHEMBL28701584 0.91 HTR1A (0.65) HTR1AMAOBHTR7HRH1DRD3
SCHEMBL28701586 0.91 HTR1A (0.65) HTR1AMAOBHTR7HRH1DRD3
SCHEMBL29459473 0.91 HTR1A (0.65) HTR1AMAOBHTR7HRH1DRD3
SCHEMBL29459577 0.91 HTR1A (0.65) HTR1AMAOBHTR7HRH1DRD3
SCHEMBL13469510 0.87 HTR1A (0.79) HTR1AMAOBDRD3DRD2
SCHEMBL5113354 0.86 HTR1A (0.61) HTR1AMAOBHTR7HRH1DRD3
SCHEMBL7989673 0.84 HTR1A (0.62) HTR1AMAOBHTR7DRD3ALDH1A1
SCHEMBL1569172 0.83 HTR1A (0.69) HTR1AMAOBDRD3DRD2
SCHEMBL14028451 0.83 HTR1A (0.79) HTR1AMAOBDRD3DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547672-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2025-05-07 EP disclosed
CN-119233976-A Modulators of c-MYC mRNA translation and their use in the treatment of cancer 艾尼莫生物科技公司 2024-12-31 CN disclosed
CN-114174303-B Macrocyclic compounds as STING agonists and methods and uses thereof 印度鲁宾有限公司 2024-06-25 CN disclosed
WO-2024010762-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2024-01-11 WO disclosed
EP-4004002-A1 MACROCYCLIC COMPOUNDS AS STING AGONISTS AND METHODS AND USES THEREOF Lupin Limited (IN) 2022-06-01 EP disclosed
CN-114174303-A Macrocyclic compounds as STING agonists, methods and uses thereof 印度鲁宾有限公司 2022-03-11 CN disclosed