SCHEMBL29459696

SCHEMBL29459696

Nc1ncnc2c1ncn2[C@@]1(F)C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 2/20 0.56
ADORA3 P0DMS8 7/20 0.54
ADORA2A P29274 5/20 0.54
GMPS P49915 1/20 0.48
PI4KA P42356 3/20 0.48
PI4K2B Q8TCG2 3/20 0.48
PI4K2A Q9BTU6 3/20 0.48
PI4KB Q9UBF8 3/20 0.48
ADORA2B P29275 2/20 0.48
DPP4 P27487 1/20 0.48
MEN1 O00255 1/20 0.48
MAP3K7 O43318 1/20 0.48
SLC28A2 O43868 1/20 0.48
GAPDH P04406 1/20 0.48
MAPK1 P28482 1/20 0.48
ADORA1 P30542 1/20 0.48
STAT6 P42226 1/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
DOT1L Q8TEK3 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3466617 1.00 SLC28A1 (0.56) SLC28A1ADORA3ADORA2AGMPSPI4KA
SCHEMBL30671963 0.91 SLC28A1 (0.52) SLC28A1ADORA3ADORA2AGMPSPI4KA
SCHEMBL27220667 0.87 SLC28A1 (0.42) SLC28A1ADORA3ADORA2AGMPSPI4KA
SCHEMBL29406372 0.87 SLC28A1 (0.42) SLC28A1ADORA3ADORA2AGMPSPI4KA
SCHEMBL30639792 0.85 AHCY (0.44) SLC28A1ADORA3ADORA2AADORA2BADORA1
SCHEMBL9956204 0.85 SLC28A1 (0.57) SLC28A1ADORA3ADORA2AGMPSPI4KA
SCHEMBL6756465 0.85 SLC28A1 (0.57) SLC28A1ADORA3ADORA2AGMPSPI4KA
SCHEMBL29362292 0.85 SLC28A1 (0.57) SLC28A1ADORA3ADORA2AGMPSPI4KA
SCHEMBL2335292 0.85 SLC28A1 (0.57) SLC28A1ADORA3ADORA2AGMPSPI4KA
SCHEMBL66047 0.84 SLC28A1 (0.56) SLC28A1ADORA3ADORA2AGMPSPI4KA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447532-B Purification method of 2 '-fluoro-2' -deoxyadenosine 江苏申基生物科技有限公司 2026-05-12 CN claimed
CN-119351366-A N-deoxyribotransferase mutant and application thereof in synthesis of 2 '-fluoro-2' -deoxyadenosine analogue 上海合全药物研发有限公司 2025-01-24 CN claimed
CN-117568426-A Method for synthesizing 2 '-fluoro-2' -deoxyadenosine by whole cell catalysis 武汉糖智药业有限公司 2024-02-20 CN claimed
CN-117447532-A Purification method of 2 '-fluoro-2' -deoxyadenosine 江苏申基生物科技有限公司 2024-01-26 CN claimed
CN-115725676-A Enzymatic synthesis method of modified nucleoside 江苏海洋大学 2023-03-03 CN claimed
CN-111534493-B Purine nucleoside phosphorylase mutant, gene and application 浙江大学宁波理工学院 2022-03-29 CN claimed
CN-113396219-B Purification of mRNA by tangential flow filtration ETHRIS GMBH (DE) 2026-05-26 CN disclosed
CN-117447532-B Purification method of 2 '-fluoro-2' -deoxyadenosine 江苏申基生物科技有限公司 2026-05-12 CN disclosed
CN-117447532-B Purification method of 2 '-fluoro-2' -deoxyadenosine 江苏申基生物科技有限公司 2026-05-12 CN disclosed
CN-117447532-B Purification method of 2 '-fluoro-2' -deoxyadenosine 江苏申基生物科技有限公司 2026-05-12 CN disclosed
CN-119410602-B 5' -Methylthioadenosine phosphorylase mutant and application thereof 河北工业大学 2025-09-26 CN disclosed
CN-120138086-A Process for preparing nucleoside analogues 正大天晴药业集团股份有限公司 2025-06-13 CN disclosed
CN-120129532-A Stabilized lipid or lipid nanoparticle suspensions 埃泽瑞斯公司 2025-06-10 CN disclosed
CN-110234656-B Exonucleotidase inhibitors and methods of use thereof 卡利泰拉生物科技公司 2023-02-28 CN disclosed
WO-2023288111-A2 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR GENE EXPRESSION REGULATION APTAH BIO, INC. (US) 2023-01-19 WO disclosed
WO-2022269346-A2 COMPOSITIONS AND METHODS OF MODULATING XANTHINE DEHYDROGENASE HORIZON THERAPEUTICS IRELAND DAC (IE) 2022-12-29 WO disclosed
WO-2022226377-A1 COMPOSITIONS AND METHODS FOR MODULATING SOS GENE EXPRESSIONS MOLECULAR AXIOM, LLC (US) 2022-10-27 WO disclosed
WO-2022175684-A1 MODIFIED ADENINES NUCLERA NUCLEICS LTD (GB) 2022-08-25 WO disclosed
CN-111534493-B Purine nucleoside phosphorylase mutant, gene and application 浙江大学宁波理工学院 2022-03-29 CN disclosed
WO-2022061163-A1 METHODS, SYSTEMS AND DEVICES FOR POST-FABRICATION DRUG LOADING THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2022-03-24 WO disclosed