Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24783371 | 1.00 | NPC1 (0.34) | NPC1F2RL1DGAT1MAPT | |
| SCHEMBL25021669 | 0.84 | NPC1 (0.34) | NPC1F2RL1DGAT1MAPT | |
| SCHEMBL19616675 | 0.82 | DGAT1 (0.37) | NPC1DGAT1 | |
| SCHEMBL26348707 | 0.79 | NPC1 (0.37) | NPC1DGAT1 | |
| SCHEMBL29459977 | 0.79 | NPC1 (0.34) | NPC1F2RL1DGAT1 | |
| SCHEMBL24783373 | 0.79 | NPC1 (0.34) | NPC1F2RL1DGAT1 | |
| SCHEMBL24783374 | 0.79 | NPC1 (0.36) | NPC1F2RL1DGAT1MAPT | |
| SCHEMBL29460036 | 0.79 | NPC1 (0.36) | NPC1F2RL1DGAT1MAPT | |
| SCHEMBL20746046 | 0.78 | MAPT (0.34) | NPC1F2RL1DGAT1MAPT | |
| SCHEMBL31276772 | 0.77 | DGAT1 (0.37) | NPC1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022067462-A1 | PROCESS FOR PREPARING INHIBITORS OF KRAS G12C | BEIGENE (BEIJING) CO., LTD. (CN) | 2022-04-07 | — | — | WO | disclosed |