Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 1.00 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.74 |
| ▸ | HTR2C | P28335 | 2/20 | 0.62 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | HTR7 | P34969 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | PTPRC | P08575 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503767 | 1.00 | SRD5A2 (1.00) | SRD5A2SRD5A1HTR2CHTR2BDRD2 | |
| Cyanide SCHEMBL11194392 | 0.95 | SRD5A2 (0.90) | SRD5A2SRD5A1HTR2CHTR2BDRD2 | |
| SCHEMBL31069845 | 0.93 | SRD5A2 (0.86) | SRD5A2SRD5A1HTR2CHTR2BDRD2 | |
| SCHEMBL29709873 | 0.93 | SRD5A2 (0.86) | SRD5A2SRD5A1HTR2CHTR2BDRD2 | |
| SCHEMBL3105349 | 0.93 | SRD5A2 (0.86) | SRD5A2SRD5A1HTR2CHTR2BDRD2 | |
| SCHEMBL16126108 | 0.91 | SRD5A2 (0.84) | SRD5A2SRD5A1HTR2CHTR2BDRD2 | |
| SCHEMBL28119578 | 0.91 | SRD5A2 (0.83) | SRD5A2SRD5A1HTR2CHTR2BDRD2 | |
| SCHEMBL31456551 | 0.90 | SRD5A2 (0.81) | SRD5A2SRD5A1HTR2CHTR2BDRD2 | |
| SCHEMBL27506 | 0.90 | SRD5A2 (0.81) | SRD5A2SRD5A1HTR2CHTR2BDRD2 | |
| SCHEMBL30976964 | 0.89 | SRD5A2 (0.79) | SRD5A2SRD5A1HTR2CHTR2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3953350-A1 | D3 RECEPTOR AGONIST COMPOUNDS; METHODS OF PREPARATION; INTERMEDIATES THEREOF; AND METHODS OF USE THEREOF | The United States of America, as Represented by The Department of Health and Human Services (US) | 2022-02-16 | — | — | EP | disclosed |