SCHEMBL503767

SCHEMBL503767

O=C(O)c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 5/20 1.00
SRD5A1 P18405 4/20 0.74
HTR2C P28335 2/20 0.62
HTR2B P41595 2/20 0.62
DRD2 P14416 1/20 0.62
ADRA1D P25100 1/20 0.62
HTR2A P28223 1/20 0.62
HTR7 P34969 1/20 0.62
ADRA1A P35348 1/20 0.62
ADRA1B P35368 1/20 0.62
ALDH1A1 P00352 3/20 0.62
CYP1A2 P05177 2/20 0.62
HPGD P15428 2/20 0.62
RAB9A P51151 3/20 0.56
NPC1 O15118 2/20 0.56
MAPT P10636 2/20 0.56
TTR P02766 1/20 0.55
PTPRC P08575 2/20 0.53
ADRA2A P08913 1/20 0.53
MAOA P21397 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29460235 1.00 SRD5A2 (1.00) SRD5A2SRD5A1HTR2CHTR2BDRD2
Cyanide SCHEMBL11194392 0.95 SRD5A2 (0.90) SRD5A2SRD5A1HTR2CHTR2BDRD2
SCHEMBL31069845 0.93 SRD5A2 (0.86) SRD5A2SRD5A1HTR2CHTR2BDRD2
SCHEMBL29709873 0.93 SRD5A2 (0.86) SRD5A2SRD5A1HTR2CHTR2BDRD2
SCHEMBL3105349 0.93 SRD5A2 (0.86) SRD5A2SRD5A1HTR2CHTR2BDRD2
SCHEMBL16126108 0.91 SRD5A2 (0.84) SRD5A2SRD5A1HTR2CHTR2BDRD2
SCHEMBL28119578 0.91 SRD5A2 (0.83) SRD5A2SRD5A1HTR2CHTR2BDRD2
SCHEMBL27506 0.90 SRD5A2 (0.81) SRD5A2SRD5A1HTR2CHTR2BDRD2
SCHEMBL31456551 0.90 SRD5A2 (0.81) SRD5A2SRD5A1HTR2CHTR2BDRD2
SCHEMBL30976964 0.89 SRD5A2 (0.79) SRD5A2SRD5A1HTR2CHTR2BDRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108176147-B Lathe oil mist adsorbs recovery unit 宁波艾格玛机电科技有限公司 2020-08-11 CN claimed
US-7842696-B2 Piperazine derivatives as inhibitors of stearoyl-CoA desaturase FOREST LABORATORIES HOLDINGS LIMITED (BM) 2010-11-30 US claimed
US-20090221583-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE FOREST LABORATORIES HOLDINGS LIMITED (BM) 2009-09-03 US claimed
CN-1166704-C Anti-reflection coating polymer and preparing method thereof �ִ����Ӳ�ҵ��ʽ���� 2004-09-15 CN claimed
US-6492441-B2 DIAZONAPTHOQUINONESULFONYL-SUBSTITUTED POLYMER SUITABLE FOR USE IN ANTI-REFLECTIVE COATING OF A SEMICONDUCTOR DEVICE HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-12-10 US claimed
US-20020120070-A1 Anti reflective coating polymers and the preparation method thereof HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2002-08-29 US claimed
CN-1260355-A Anti-reflection coating polymer and preparing method thereof HYUNDAI ELECTRONICS IND (KR) 2000-07-19 CN claimed
US-20250376385-A1 PEROVSKITE POWDER, LIGHT EMITTING LAYER FOR LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING THE SAME SEOUL NAT UNIV R&DB FOUNDATION (KR) 2025-12-11 US disclosed
US-12479838-B2 D3 receptor agonist compounds; methods of preparation; intermediates thereof; and methods of use thereof THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2025-11-25 US disclosed
CN-120136251-A Method for producing hydroxyl free radical by high-efficiency low-energy consumption chemistry 上海交通大学 2025-06-13 CN disclosed
US-20240269293-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF OD THERAPEUTICS LIMITED (CN) 2024-08-15 US disclosed
EP-4313154-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF OD Therapeutics Limited (HK) 2024-02-07 EP disclosed
CN-117355337-A Protein-macromolecule conjugates and methods of use thereof 奥迪曼药业科技有限公司 2024-01-05 CN disclosed
US-5182316-A Forming a UV-detectable fluorophore in a mixture of hydride containing silicone, unsaturated silicone, cationically sensitive compound and a latent dibenzofulvene MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-01-26 US disclosed
US-5118559-A Dibenzofulvene compound MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-06-02 US disclosed
WO-1992000995-A1 CYCLIC CELL ADHESION MODULATION COMPOUNDS TANABE SEIYAKU CO. LTD. (JP) 1992-01-23 WO disclosed
US-5047444-A Hydrosilatable polysiloxanes, unsaturated compounds and a dibenzofulvene chromogen; coatings MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-09-10 US disclosed
EP-0400972-A2 Fluorescent degree of cure monitors MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-12-05 EP disclosed
US-4052436-A ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1977-10-04 US disclosed
US-3989841-A ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1976-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240269293-A1 PROTEIN-MACROMOLECULE CONJUGATES AND METHODS OF USE THEREOF CD44, MACROD1, MSN SRD5A2 4748/4885SRD5A1 4745/4885HTR2C 3784/4885
US-12479838-B2 D3 receptor agonist compounds; methods of preparation; intermediates thereof; and methods of use thereof DRD3, ADRB3, VDR SRD5A2 704/4885SRD5A1 884/4885HTR2C 78/4885
US-20090221583-A1 NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE SCD, SCD5, FADS2 SRD5A2 594/4885SRD5A1 558/4885HTR2C 3359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.