SCHEMBL29460684

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CS)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)CNC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)CN)[C@@H](C)O)[C@@H](C)O)[C@@H](C)CC)C(C)C)[C@@H](C)CC)[C@@H](C)O)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	19/20	0.68

▸	KEAP1	Q14145	1/20	0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31182987	0.93	GLP1R (0.71)	GLP1RKEAP1
SCHEMBL30721560	0.91	GLP1R (0.76)	GLP1R
SCHEMBL31182955	0.91	KEAP1 (0.65)	GLP1RKEAP1
SCHEMBL30422899	0.90	GLP1R (0.72)	GLP1RKEAP1
SCHEMBL30431387	0.90	GLP1R (0.71)	GLP1R
SCHEMBL30658299	0.89	KEAP1 (0.69)	GLP1RKEAP1
SCHEMBL31182950	0.89	GLP1R (0.72)	GLP1R
SCHEMBL31500843	0.88	GLP1R (0.76)	GLP1R
SCHEMBL31099260	0.88	GLP1R (0.81)	GLP1R
SCHEMBL31243565	0.88	GLP1R (0.73)	GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240269300-A1	METHODS OF USING GLYCOPOLYSIALYLATED THERAPEUTIC PROTEINS	XENETIC BIOSCIENCES, INC. (US)	2024-08-15	—	—	US	disclosed
US-20220105190-A1	METHODS OF USING GLYCOPOLYSIALYLATED THERAPEUTIC PROTEINS	LIPOXEN TECHNOLOGIES LIMITED (US)	2022-04-07	—	—	US	disclosed