Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.49 |
| ▸ | MPL | P40238 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150692 | 1.00 | KMT2A (0.49) | KMT2AMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL29351257 | 1.00 | KMT2A (0.49) | KMT2AMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL593620 | 0.98 | KMT2A (0.48) | KMT2AMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL593622 | 0.98 | KMT2A (0.48) | KMT2AMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL15849895 | 0.88 | ALDH1A1 (0.44) | KMT2AMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL305044 | 0.82 | CYP1A2 (0.44) | KMT2AMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL29440271 | 0.82 | KDM4E (0.38) | KMT2AMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL22125496 | 0.82 | KDM4E (0.38) | KMT2AMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL29440272 | 0.82 | KDM4E (0.38) | KMT2AMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL10076070 | 0.81 | HSD17B10 (0.42) | KMT2AMAPK1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719473-A1 | METHODS, SYSTEMS, AND KITS FOR TREATMENT OF INFLAMMATORY DISEASES BY TARGETING TL1A | Prometheus Biosciences, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-4630578-A1 | MULTIPLEXED DETECTION OF NUCLEIC ACID TARGETS | Advanced Cell Diagnostics, Inc. (US) | 2025-10-15 | — | — | EP | disclosed |
| EP-4623098-A1 | SYSTEMS, METHODS, AND KITS FOR DETECTING PROTEIN INTERACTIONS | Advanced Cell Diagnostics, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| EP-4561624-A1 | METHODS FOR TREATING PATIENTS WITH LOCALLY ADVANCED OR METASTATIC UROTHELIAL CANCER WITH ANTIBODY DRUG CONJUGATES (ADC) THAT BIND 191P4D12 PROTEINS IN COMBINATION WITH PEMBROLIZUMAB | Agensys, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-119907684-A | Methods of treating patients with locally advanced or metastatic urothelial cancer with an Antibody Drug Conjugate (ADC) that binds 191P4D12 protein in combination with palbociclib | 艾更斯司股份有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-119855920-A | Method for detecting target nucleic acid using RNA blocking molecule | 领先细胞医疗诊断有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-119838023-A | Methods of treating myometrial invasive urothelial cancer or myometrial invasive bladder cancer with Antibody Drug Conjugates (ADC) that bind to 191P4D12 protein | 艾更斯司股份有限公司 | 2025-04-18 | — | — | CN | disclosed |
| WO-2025064741-A1 | TREATING LOCALLY ADVANCED OR METASTATIC UROTHELIAL CANCER WITH ANTI-191P4D12 ANTIBODY DRUG CONJUGATES IN COMBINATION WITH PEMBROLIZUMAB | AGENSYS, INC. (US) | 2025-03-27 | — | — | WO | disclosed |
| WO-2024249282-A1 | METHODS, SYSTEMS, AND KITS FOR TREATMENT OF INFLAMMATORY DISEASES BY TARGETING TL1A | PROMETHEUS BIOSCIENCES, INC. (US) | 2024-12-05 | — | — | WO | disclosed |
| EP-4466375-A2 | METHODS FOR DETECTING PROTEINS AND FOR CO-DETECTING PROTEINS AND NUCLEIC ACIDS, AND KITS FOR THE SAME | Advanced Cell Diagnostics, Inc. (US) | 2024-11-27 | — | — | EP | disclosed |
| EP-4147044-A1 | METHODS FOR SIMULTANEOUSLY DETECTING TARGET NUCLEIC ACIDS AND PROTEINS AND A KIT THEREOF | Advanced Cell Diagnostics, Inc. (US) | 2023-03-15 | — | — | EP | disclosed |
| EP-4132942-A1 | IN SITU METHODS FOR DETECTING TARGET NUCLEIC ACIDS BYHYBRIDIZATION AND A KIT THEREOF | Advanced Cell Diagnostics, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| CN-115702349-A | Method for simultaneously detecting target nucleic acid and protein and kit therefor | 领先细胞医疗诊断有限公司 | 2023-02-14 | — | — | CN | disclosed |
| EP-4114967-A1 | METHODS FOR DETECTING NTRK GENE FUSION USING RNA IN SITU HYBRIDIZATION | Advanced Cell Diagnostics, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |
| WO-2022269534-A1 | USE OF SINGLE CELL ELISA STARTING FROM DEPARAFFINZED CELLS FOR THE DETECTION OF MOLECULES OF INTEREST | JANSSEN BIOTECH, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| EP-4061958-A1 | METHODS FOR SEQUENTIAL DETECTION OF NUCLEIC ACIDS | Advanced Cell Diagnostics, Inc. (US) | 2022-09-28 | — | — | EP | disclosed |
| CN-114945681-A | Method for continuous nucleic acid detection | 领先细胞医疗诊断有限公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114555825-A | Method for multiplexed detection of nucleic acids by in situ hybridization | 领先细胞医疗诊断有限公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2022076767-A1 | METHODS FOR TREATING CANCERS WITH ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS | AGENSYS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |
| WO-2022060955-A1 | METHODS FOR TREATING CANCERS WITH ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS | AGENSYS, INC. (US) | 2022-03-24 | — | — | WO | disclosed |