Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.60 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.60 |
| ▸ | GNPAT | O15228 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.55 |
| ▸ | CHRNG | P07510 | 1/20 | 0.55 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.55 |
| ▸ | CHRND | Q07001 | 1/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | NPY4R | P50391 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30712028 | 1.00 | ERAP2 (0.60) | ERAP2LNPEPGNPATOPRK1CHRNA1 | |
| SCHEMBL30523241 | 1.00 | ERAP2 (0.60) | ERAP2LNPEPGNPATOPRK1CHRNA1 | |
| SCHEMBL31347785 | 1.00 | ERAP2 (0.60) | ERAP2LNPEPGNPATOPRK1CHRNA1 | |
| SCHEMBL30591078 | 1.00 | ERAP2 (0.60) | ERAP2LNPEPGNPATOPRK1CHRNA1 | |
| SCHEMBL31474739 | 1.00 | ERAP2 (0.60) | ERAP2LNPEPGNPATOPRK1CHRNA1 | |
| SCHEMBL29641060 | 0.97 | NPY1R (0.58) | ERAP2LNPEPGNPATOPRK1CHRNA1 | |
| SCHEMBL30523264 | 0.97 | LNPEP (0.63) | ERAP2LNPEPGNPATOPRK1CHRNA1 | |
| SCHEMBL29577087 | 0.96 | NPY4R (0.59) | ERAP2LNPEPGNPATCHRNA1CHRNG | |
| SCHEMBL29576811 | 0.96 | NPY4R (0.59) | ERAP2LNPEPGNPATCHRNA1CHRNG | |
| SCHEMBL30931517 | 0.95 | LNPEP (0.62) | ERAP2LNPEPGNPATOPRK1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496356-A | CXCR4 specific molecular imaging probe and preparation method and application thereof | 上海交通大学医学院附属仁济医院 | 2023-07-28 | — | — | CN | claimed |
| CN-116457028-A | Novel CXCR4 targeting compounds | 省卫生服务机构 | 2023-07-18 | — | — | CN | claimed |
| CN-114364690-A | Novel radiolabeled CXCR4 targeting compounds for diagnosis and therapy | 省卫生服务机构 | 2022-04-15 | — | — | CN | claimed |
| CN-119661653-A | CXCR4 targeted diagnostic and therapeutic agents with reduced species selectivity | 慕尼黑工业大学 | 2025-03-21 | — | — | CN | disclosed |
| CN-112673015-B | CXCR4 targeted diagnostic and therapeutic agents with reduced species selectivity | 慕尼黑工业大学 | 2025-01-07 | — | — | CN | disclosed |
| CN-117042812-A | CXCR 4-ligands and precursors thereof for diagnostic and therapeutic uses | 慕尼黑工业大学 | 2023-11-10 | — | — | CN | disclosed |
| CN-116496356-A | CXCR4 specific molecular imaging probe and preparation method and application thereof | 上海交通大学医学院附属仁济医院 | 2023-07-28 | — | — | CN | disclosed |
| CN-116457028-A | Novel CXCR4 targeting compounds | 省卫生服务机构 | 2023-07-18 | — | — | CN | disclosed |
| CN-113150068-B | Peptide compound, application thereof and composition containing peptide compound | 尚华医药科技(江西)有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-114364690-A | Novel radiolabeled CXCR4 targeting compounds for diagnosis and therapy | 省卫生服务机构 | 2022-04-15 | — | — | CN | disclosed |
| CN-114364690-A | Novel radiolabeled CXCR4 targeting compounds for diagnosis and therapy | 省卫生服务机构 | 2022-04-15 | — | — | CN | disclosed |