SCHEMBL2946256

SCHEMBL2946256

CCCCCCOC(=O)c1c(CC)cccc1C(=O)OCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.68
TSHR P16473 4/20 0.68
L3MBTL1 Q9Y468 4/20 0.68
CYP3A4 P08684 3/20 0.68
TDP1 Q9NUW8 3/20 0.68
MAPK1 P28482 2/20 0.68
LMNA P02545 3/20 0.60
TP53 P04637 1/20 0.58
KDM4E B2RXH2 2/20 0.54
HSD17B10 Q99714 2/20 0.54
POLB P06746 1/20 0.54
MAPT P10636 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
SCN1A P35498 2/20 0.46
SCN2A Q99250 2/20 0.46
SCN3A Q9NY46 2/20 0.46
CETP P11597 3/20 0.43
MEN1 O00255 1/20 0.43
NR1I2 O75469 1/20 0.43
CHRM2 P08172 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27371803 0.93 ALDH1A1 (0.65) ALDH1A1TSHRL3MBTL1CYP3A4TDP1
SCHEMBL28030637 0.91 ALDH1A1 (0.69) ALDH1A1TSHRL3MBTL1CYP3A4TDP1
SCHEMBL11855016 0.90 ALDH1A1 (0.69) ALDH1A1TSHRL3MBTL1CYP3A4TDP1
SCHEMBL21113624 0.90 ALDH1A1 (0.69) ALDH1A1TSHRL3MBTL1CYP3A4TDP1
SCHEMBL21113714 0.89 TSHR (0.69) ALDH1A1TSHRL3MBTL1CYP3A4TDP1
SCHEMBL27769244 0.88 ALDH1A1 (0.72) ALDH1A1TSHRL3MBTL1CYP3A4TDP1
SCHEMBL509767 0.87 ALDH1A1 (0.89) ALDH1A1TSHRL3MBTL1CYP3A4TDP1
SCHEMBL7796646 0.87 ALDH1A1 (0.89) ALDH1A1TSHRL3MBTL1CYP3A4TDP1
SCHEMBL587133 0.87 ALDH1A1 (0.89) ALDH1A1TSHRL3MBTL1CYP3A4TDP1
SCHEMBL9293811 0.87 ALDH1A1 (0.89) ALDH1A1TSHRL3MBTL1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1194274-B1 PROCESS FOR THREE-DIMENSIONAL MODELING STRATASYS INC (US) 2017-03-22 EP disclosed
US-8227540-B2 Soluble material and process for three-dimensional modeling STRATASYS, INC. (US) 2012-07-24 US disclosed
US-20100270707-A1 SOULUBLE MATERIAL AND PROCESS FOR THREE-DIMENSIONAL MODELING STRATASYS, INC. (US) 2010-10-28 US disclosed
US-7754807-B2 Soluble material and process for three-dimensional modeling STRATASYS, INC. (US) 2010-07-13 US disclosed
EP-1194274-A4 SOLUBLE MATERIAL AND PROCESS FOR THREE-DIMENSIONAL MODELING STRATASYS INC (US) 2009-03-04 EP disclosed
EP-1773560-A2 SOLUBLE MATERIAL AND PROCESS FOR THREE-DIMENSIONAL MODELING STRATASYS, INC. (US) 2007-04-18 EP disclosed
WO-2006020279-A2 SOLUBLE MATERIAL AND PROCESS FOR THREE-DIMENSIONAL MODELING STRATASYS, INC. (US) 2006-02-23 WO disclosed
US-20050004282-A1 Soluble material and process for three-dimensional modeling STRATASYS, INC. (US) 2005-01-06 US disclosed
US-6790403-B1 Soluble material and process for three-dimensional modeling STRATASYS, INC. 2004-09-14 US disclosed
EP-1194274-A1 SOLUBLE MATERIAL AND PROCESS FOR THREE-DIMENSIONAL MODELING STRATASYS, INC. (US) 2002-04-10 EP disclosed
WO-2000062994-A1 SOLUBLE MATERIAL AND PROCESS FOR THREE-DIMENSIONAL MODELING STRATASYS, INC. (US) 2000-10-26 WO disclosed