Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.68 |
| ▸ | MC5R | P33032 | 2/20 | 0.68 |
| ▸ | MC3R | P41968 | 2/20 | 0.68 |
| ▸ | MC1R | Q01726 | 2/20 | 0.68 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.66 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.64 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.63 |
| ▸ | GLP1R | P43220 | 5/20 | 0.62 |
| ▸ | CXCL8 | P10145 | 5/20 | 0.61 |
| ▸ | GCGR | P47871 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361885 | 0.96 | GLP1R (0.66) | MC4RMC5RMC3RMC1RIL23R | |
| SCHEMBL31332244 | 0.95 | CXCL8 (0.64) | MC4RMC5RMC3RMC1RIL23R | |
| SCHEMBL29397826 | 0.95 | CXCL8 (0.64) | MC4RMC5RMC3RMC1RIL23R | |
| SCHEMBL29389654 | 0.93 | MC4R (0.67) | MC4RMC5RMC3RMC1RIL23R | |
| SCHEMBL29874649 | 0.91 | MC4R (0.69) | MC4RMC5RMC3RMC1RIL23R | |
| SCHEMBL18388638 | 0.88 | C5AR1 (0.74) | MC4RMC5RMC3RMC1RC5AR1 | |
| SCHEMBL31477752 | 0.88 | MC4R (0.83) | MC4RMC5RMC3RMC1RC5AR1 | |
| SCHEMBL30495708 | 0.88 | CXCR4 (0.71) | CXCR4GLP1RCXCL8GCGR | |
| SCHEMBL29581575 | 0.87 | MC4R (0.60) | MC4RMC5RMC3RMC1RIL23R | |
| Dynorphin A (1-17) SCHEMBL31331988 | 0.87 | NPY1R (0.68) | IL23RC5AR1CXCR4GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109022310-B | Bacillus Bam22 for improving resistance and growth of ryegrass and use method thereof | 四川省农业科学院植物保护研究所 | 2022-03-22 | — | — | CN | claimed |
| US-12338464-B2 | Clonal strains of attenuated vaccinia viruses and methods of use thereof | GENELUX CORPORATION (US) | 2025-06-24 | — | — | US | disclosed |
| WO-2025106999-A1 | DEPRIVATION OF HUMAN PLURIPOTENT STEM CELL-DERIVED TRPV1+, MRGPRX1+ AND SCN9A+ SENSORY NEURONS AND THEIR FUNCTIONAL CHARACTERIZATION | THE JOHNS HOPKINS UNIVERSITY (US) | 2025-05-22 | — | — | WO | disclosed |
| US-20250001013-A1 | MODULATORS OF ADENO-ASSOCIATED VIRUS TRANSDUCTION AND USES THEREOF | NOVARTIS AG (CH) | 2025-01-02 | — | — | US | disclosed |
| EP-4436982-A1 | MODULATORS OF ADENO-ASSOCIATED VIRUS TRANSDUCTION AND USES THEREOF | Novartis AG (CH) | 2024-10-02 | — | — | EP | disclosed |
| CN-118632860-A | Adeno-associated virus transduction modulators and uses thereof | 诺华股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| EP-3962510-B1 | NOVEL SELECTIVE ACKR3 MODULATORS AND USES THEREOF | LUXEMBOURG INST OF HEALTH LIH (LU) | 2024-08-28 | — | — | EP | disclosed |
| CN-114601912-B | Itching-causing polypeptide for biting of ticks and mosquitoes and application of itching-causing polypeptide in resisting itching | 武汉大学 | 2024-08-02 | — | — | CN | disclosed |
| CN-116491524-B | Application and method for controlling mulberry sclerotinia by using coniothyrium minitans | 四川省农业科学院植物保护研究所 | 2024-07-05 | — | — | CN | disclosed |
| EP-3743422-B1 | CRYSTALLINE FORMS OF THE CXCR7 RECEPTOR ANTAGONIST (3S,4S)-1-CYCLOPROPYLMETHYL-4-{[5-(2,4-DIFLUORO-PHENYL)-ISOXAZOLE-3-CARBONYL]-AMINO}-PIPERIDINE-3-CARBOXYLIC ACID (1-PYRIMIDIN-2-YL-CYCLOPROPYL)-AMIDE | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-03-13 | — | — | EP | disclosed |
| US-20220236279-A1 | Novel Selective ACKR3 Modulators and Uses Thereof | LUXEMBOURG INSTITUTE OF HEALTH (LIH) (LU) | 2022-07-28 | — | — | US | disclosed |
| WO-2022136486-A1 | CONOLIDINE ANALOGUES AS SELECTIVE ACKR3 MODULATORS FOR THE TREATMENT OF CANCER AND CARDIOVASCULAR DISEASES | LUXEMBOURG INSTITUTE OF HEALTH (LIH) (LU) | 2022-06-30 | — | — | WO | disclosed |
| CN-114601912-A | Itch-caused polypeptide caused by tick and mosquito bites and itch-resisting application thereof | 武汉大学 | 2022-06-10 | — | — | CN | disclosed |
| US-11339148-B2 | Crystalline forms of the CXCR7 receptor antagonist (3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-phenyl)-isoxazole-3-carbonyl]-amino}-piperidine-3-carboxylic acid (1-pyrimidin-2-yl-cyclopropyl)-amide | IDORSIA PHARMACEUTICALS LTD. (CH) | 2022-05-24 | — | — | US | disclosed |
| US-11306078-B2 | Piperidine CXCR7 receptor modulators | IDORSIA PHARMACEUTICALS LTD. (CH) | 2022-04-19 | — | — | US | disclosed |
| CN-114262690-A | Clonal strains of attenuated vaccinia virus and methods of use thereof | 吉恩勒克斯公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-109022310-B | Bacillus Bam22 for improving resistance and growth of ryegrass and use method thereof | 四川省农业科学院植物保护研究所 | 2022-03-22 | — | — | CN | disclosed |
| CN-109022310-B | Bacillus Bam22 for improving resistance and growth of ryegrass and use method thereof | 四川省农业科学院植物保护研究所 | 2022-03-22 | — | — | CN | disclosed |
| CN-109022310-B | Bacillus Bam22 for improving resistance and growth of ryegrass and use method thereof | 四川省农业科学院植物保护研究所 | 2022-03-22 | — | — | CN | disclosed |
| EP-3962510-A1 | NOVEL SELECTIVE ACKR3 MODULATORS AND USES THEREOF | Luxembourg Institute Of Health (LIH) (LU) | 2022-03-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11306078-B2 | Piperidine CXCR7 receptor modulators | CXCR1, CXCR5, ACKR3 | MC4R 600/4885MC5R 432/4885MC3R 416/4885 |
| US-11339148-B2 | Crystalline forms of the CXCR7 receptor antagonist (3S,4S)-1-Cyclopropylmethyl-4-{[5-(2,4-difluoro-phenyl)-isoxazole-3-carbonyl]-amino}-piperidine-3-carboxylic acid (1-pyrimidin-2-yl-cyclopropyl)-amide | CXCR1, CXCR5, CXCR4 | MC4R 423/4885MC5R 228/4885MC3R 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.