Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23045682 | 1.00 | KDM4E (0.49) | KDM4ESMN1; SMN2GAATSHRHSD17B10 | |
| SCHEMBL23045656 | 0.93 | KDM4E (0.47) | KDM4ESMN1; SMN2GAATSHRHSD17B10 | |
| SCHEMBL29463264 | 0.93 | KDM4E (0.47) | KDM4ESMN1; SMN2GAATSHRHSD17B10 | |
| SCHEMBL31383524 | 0.89 | KDM4E (0.52) | KDM4ESMN1; SMN2TSHRHSD17B10CRHBP | |
| SCHEMBL23045603 | 0.89 | KDM4E (0.52) | KDM4ESMN1; SMN2TSHRHSD17B10CRHBP | |
| SCHEMBL23045587 | 0.88 | NOD2 (0.47) | KDM4ESMN1; SMN2TSHRHSD17B10CRHBP | |
| SCHEMBL29463233 | 0.88 | NOD2 (0.47) | KDM4ESMN1; SMN2TSHRHSD17B10CRHBP | |
| SCHEMBL31383507 | 0.86 | KDM4E (0.50) | KDM4ESMN1; SMN2GAATSHRCRHBP | |
| SCHEMBL23045589 | 0.86 | KDM4E (0.50) | KDM4ESMN1; SMN2GAATSHRCRHBP | |
| SCHEMBL16733085 | 0.86 | KDM4E (0.50) | KDM4ESMN1; SMN2GAATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302874-B | Indole carboxamide derivatives and pharmaceutical compositions containing the same | 国际药品株式会社 | 2025-02-25 | — | — | CN | disclosed |
| CN-114302874-A | Indole carboxamide derivatives and pharmaceutical compositions comprising same | 国际药品株式会社 | 2022-04-08 | — | — | CN | disclosed |