Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117167 | 0.88 | KDM4E (0.58) | KDM4EABCG2ALDH1A1MAPTGAA | |
| SCHEMBL8119217 | 0.84 | AKR1B1 (0.74) | KDM4EAKR1B1ALDH1A1THRBGAA | |
| SCHEMBL4254491 | 0.84 | KDM4E (0.72) | KDM4EAKR1B1ALDH1A1THRBMAPT | |
| SCHEMBL8107875 | 0.82 | KDM4E (1.00) | KDM4EAKR1B1ALDH1A1MAPTGAA | |
| SCHEMBL9635473 | 0.82 | KDM4E (0.70) | KDM4EABCG2AKR1B1ALDH1A1THRB | |
| SCHEMBL18397901 | 0.81 | AKR1B1 (0.69) | KDM4EAKR1B1ALDH1A1POLBKMT2A | |
| SCHEMBL3397825 | 0.80 | MAPT (0.68) | KDM4EABCG2ALDH1A1MAPTGAA | |
| SCHEMBL29463595 | 0.80 | MAPT (0.68) | KDM4EABCG2ALDH1A1MAPTGAA | |
| SCHEMBL13903598 | 0.80 | PIM1 (0.49) | KDM4EABCG2ALDH1A1MAPTKMT2A | |
| SCHEMBL29588216 | 0.80 | PIM1 (0.49) | KDM4EABCG2ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022036040-A1 | SYNTHESIS OF SMALL MOLECULES INSPIRED BY PHOMOXANTHONE A | WORCESTER POLYTECHNIC INSTITUTE (US) | 2022-02-17 | — | — | WO | disclosed |