Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | TNKS | O95271 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3837934 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1MAOBHPGDCYP3A4 | |
| SCHEMBL8827792 | 0.87 | KDM4E (0.78) | KDM4EALDH1A1MAOBHPGDCYP3A4 | |
| SCHEMBL8107014 | 0.86 | KDM4E (0.76) | KDM4EALDH1A1TSHRMAOBHPGD | |
| SCHEMBL5322779 | 0.86 | KDM4E (0.76) | KDM4EALDH1A1MAOBHPGDCYP3A4 | |
| SCHEMBL8107902 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1TSHRMAOBHPGD | |
| SCHEMBL4254491 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1MAOBHPGDMAPT | |
| SCHEMBL8119217 | 0.84 | AKR1B1 (0.74) | KDM4EALDH1A1MAOBHPGDCYP3A4 | |
| SCHEMBL29463588 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1TSHRMAOBHPGD | |
| SCHEMBL9635473 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1TSHRMAOBHPGD | |
| SCHEMBL29463590 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1TSHRCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634409-B1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL CO (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5659051-A | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0634409-A1 | Process of producing 2-cyano-4-oxo-4H-benzopyran compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-18 | — | — | EP | disclosed |