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Sugi Predict / Compounds / SCHEMBL2946392

SCHEMBL2946392

SCHEMBL2946392

Cc1c(C(=O)O)nn(-c2ccc(Cl)cc2Cl)c1OS(=O)(=O)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.47
▸ CNR2 P34972 10/20 0.44
▸ CNR1 P21554 7/20 0.44
▸ MARS1 P56192 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14195813 0.91 CNR2 (0.45) LMNACNR2CNR1
SCHEMBL30961542 0.89 KDM4E (0.56) CNR2CNR1
SCHEMBL4831613 0.89 KDM4E (0.56) CNR2CNR1
SCHEMBL14195805 0.81 KDM4E (0.50) CNR2CNR1
SCHEMBL14195811 0.80 CNR2 (0.41) CNR2CNR1
SCHEMBL13955259 0.77 LMNA (0.67) LMNACNR2CNR1
SCHEMBL24238342 0.74 CNR1 (0.61) CNR2CNR1
SCHEMBL30961565 0.74 CNR1 (0.61) CNR2CNR1
SCHEMBL2874075 0.74 CNR2 (0.63) CNR2CNR1MARS1
SCHEMBL4611583 0.74 CNR2 (0.58) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1753726-B1 METHOD FOR PRODUCING 1,5-DIPHENYLPYRAZOLE CARBOXYLIC ACID DERIVATIVES SANOFI AVENTIS (FR) 2010-01-06 — — EP disclosed
EP-1753726-A1 METHOD FOR PRODUCING 1,5-DIPHENYLPYRAZOLE CARBOXYLIC ACID DERIVATIVES Sanofi-Aventis (FR) 2007-02-21 — — EP disclosed
WO-2005115989-A1 METHOD FOR PRODUCING 1,5-DIPHENYLPYRAZOLE CARBOXYLIC ACID DERIVATIVES SANOFI-AVENTIS (FR) 2005-12-08 — — WO disclosed