SCHEMBL29464263

SCHEMBL29464263

c1ncc2nc3nnncc3nc2n1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 1/20 0.38
EGFR P00533 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3292267 0.82 PIK3CG (0.47) PIK3CGEGFR
SCHEMBL16878170 0.77 EGFR (0.35) EGFR
SCHEMBL30826363 0.77 EGFR (0.35) EGFR
SCHEMBL1378685 0.75 PIK3CG (0.46) PIK3CGEGFR
SCHEMBL30148832 0.74 EGFR (0.37) EGFR
SCHEMBL374489 0.74 EGFR (0.37) EGFR
SCHEMBL30611771 0.72 PIK3CG (0.41) PIK3CGEGFR
SCHEMBL30124132 0.71 EGFR (0.54) PIK3CGEGFR
SCHEMBL35632 0.71 EGFR (0.54) PIK3CGEGFR
SCHEMBL30290978 0.68 PIK3CG (0.41) PIK3CGEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790087-B Deuterated fused-ring compounds, polymers, mixtures, compositions, and organic electronic devices 广州华睿光电材料有限公司 2022-03-18 CN disclosed