Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 3/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30124132 | 1.00 | EGFR (0.54) | EGFRMAPTPIK3CGPIK3CDPIK3CA | |
| SCHEMBL3292267 | 0.86 | PIK3CG (0.47) | EGFRPIK3CGPIK3CDPIK3CAALDH1A1 | |
| SCHEMBL31214569 | 0.86 | NQO2 (0.50) | EGFRMAPTPIK3CGPIK3CDPIK3CA | |
| SCHEMBL1378685 | 0.84 | PIK3CG (0.46) | EGFRPIK3CGALDH1A1METAP2METAP1 | |
| SCHEMBL2049528 | 0.83 | EGFR (0.45) | EGFRMAPTPIK3CGPIK3CDPIK3CA | |
| SCHEMBL10353335 | 0.82 | PIK3CG (0.44) | EGFRMAPTPIK3CGPIK3CDPIK3CA | |
| SCHEMBL22589760 | 0.80 | PLAUR (0.47) | EGFRPIK3CGALDH1A1KDM4EHPGD | |
| SCHEMBL4445369 | 0.78 | LMNA (0.60) | EGFRMAPTPIK3CGPIK3CDPIK3CA | |
| SCHEMBL3536096 | 0.76 | PIK3CG (0.67) | EGFRPIK3CGALDH1A1KDM4EHPGD | |
| SCHEMBL30611771 | 0.76 | PIK3CG (0.41) | EGFRPIK3CGMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572258-A | C 2 Preparation method of axial chiral biquinoline framework compound | 中国科学院成都有机化学有限公司 | 2023-01-06 | — | — | CN | claimed |
| CN-115403523-A | Biquinoline-aryl phenol framework compound with axial chirality and preparation method and application thereof | 中国科学院成都有机化学有限公司 | 2022-11-29 | — | — | CN | claimed |
| CN-115403522-A | Biphenyl quinoline skeleton compound with C2 axis chirality, chiral isomer thereof, preparation method and application thereof | 中国科学院成都有机化学有限公司 | 2022-11-29 | — | — | CN | claimed |
| CN-108676007-B | Radionuclide-labeled benzopteridine derivative and preparation method and application thereof | 厦门大学 | 2020-06-26 | — | — | CN | claimed |
| EP-1719200-B1 | HIGH-PERFORMANCE MEMBRANE ELECTRODE UNIT AND THE USE THEREOF IN FUEL CELLS | BASF FUEL CELL RES GMBH (DE) | 2017-08-30 | — | — | EP | claimed |
| EP-2336315-B1 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION AS (DK) | 2017-07-19 | — | — | EP | claimed |
| EP-2336315-A2 | Enzymatic encoding methods for efficient synthesis of large libraries | Nuevolution A/S (DK) | 2011-06-22 | — | — | EP | claimed |
| US-20080194821-A1 | Light Emitting Compound for Electroluminescent Applications | TECHNISCHE UNIVERSITAET BRAUNCHWEIG (DE) | 2008-08-14 | — | — | US | claimed |
| EP-1883687-A1 | LIGHT EMITTING COMPOUND FOR ELECTROLUMINESCENT APPLICATIONS | Technische Universität Braunschweig (DE) | 2008-02-06 | — | — | EP | claimed |
| WO-2006119800-A1 | LIGHT EMITTING COMPOUND FOR ELECTROLUMINESCENT APPLICATIONS | TECHNISCHE UNIVERSITÄT BRAUNSCHWEIG (DE) | 2006-11-16 | — | — | WO | claimed |
| EP-0579835-A1 | WAVELENGTH CONVERSION MATERIAL FOR AGRICULTURE | NIPPON SODA CO., LTD. (JP) | 1994-01-26 | — | — | EP | claimed |
| JP-6040817-A | — | — | None | — | — | JP | disclosed |
| US-20240124405-A1 | REDOX-ACTIVE COMPOUNDS AND USES THEREOF | CMBLU PROJECKT AG (DE) | 2024-04-18 | — | — | US | disclosed |
| US-11952457-B2 | Bioabsorbable resin for additive manufacturing with non-cytotoxic photoinitiator | CARBON, INC. (US) | 2024-04-09 | — | — | US | disclosed |
| US-20240065990-A1 | METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID | BELLUS HEALTH INC (CA) | 2024-02-29 | — | — | US | disclosed |
| EP-0383759-A4 | N?6 -SUBSTITUTED 9-METHYLADENINES: A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS | — | 1993-03-17 | — | — | EP | disclosed |
| US-5066655-A | Inhibiting adenylate cyclase | WHITBY RESEARCH, INC. (US) | 1991-11-19 | — | — | US | disclosed |
| US-4959212-A | ENZYMES AND COENZYMES | STANCESCO ALEXANDRA (US) | 1990-09-25 | — | — | US | disclosed |
| EP-0383759-A1 | N6 SUBSTITUTED 9-METHYLADENINES: A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS | Whitby Research Incorporated (US) | 1990-08-29 | — | — | EP | disclosed |
| WO-1988008303-A1 | N6-SUBSTITUTED 9-METHYLADENINES: A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS | NELSON RESEARCH AND DEVELOPMENT COMPANY (US) | 1988-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194821-A1 | Light Emitting Compound for Electroluminescent Applications | NR2E3, DRD3, OCIAD2 | EGFR 185/4885MAPT 1933/4885PIK3CG 4593/4885 |
| US-20240065990-A1 | METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID | APP, PSEN1, PSEN2 | EGFR 1419/4885MAPT 22/4885PIK3CG 1252/4885 |
| US-20240124405-A1 | REDOX-ACTIVE COMPOUNDS AND USES THEREOF | NOX4, NQO1, GPX1 | EGFR 4620/4885MAPT 1567/4885PIK3CG 1168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.