Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 19/20 | 0.42 |
| ▸ | ATRIP | Q8WXE1 | 13/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 8/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 7/20 | 0.40 |
| ▸ | MTOR | P42345 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19951339 | 1.00 | ATR (0.42) | ATRATRIPPDCD1CD274CHEK1 | |
| SCHEMBL19951337 | 1.00 | ATR (0.42) | ATRATRIPPDCD1CD274CHEK1 | |
| SCHEMBL19951347 | 0.87 | PIK3C3 (0.42) | ATRATRIPPDCD1CD274CHEK1 | |
| SCHEMBL19951349 | 0.87 | PIK3C3 (0.42) | ATRATRIPPDCD1CD274CHEK1 | |
| SCHEMBL29464382 | 0.87 | PIK3C3 (0.42) | ATRATRIPPDCD1CD274CHEK1 | |
| SCHEMBL23770699 | 0.84 | ATR (0.45) | ATRATRIPPDCD1CD274MTOR | |
| SCHEMBL19951388 | 0.81 | GHSR (0.39) | — | |
| SCHEMBL28713921 | 0.78 | SCN9A (0.36) | — | |
| SCHEMBL19951355 | 0.77 | ATR (0.42) | ATRATRIPPDCD1CD274CHEK1 | |
| SCHEMBL29464489 | 0.77 | ATR (0.42) | ATRATRIPPDCD1CD274CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |