Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 13/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925212 | 1.00 | LMNA (0.43) | LMNAMEN1KMT2ASMN1; SMN2SMO | |
| SCHEMBL19925152 | 0.91 | SMO (0.41) | LMNASMOKDM4EHSD17B10 | |
| SCHEMBL29464403 | 0.91 | SMO (0.41) | LMNASMOKDM4EHSD17B10 | |
| SCHEMBL19968812 | 0.88 | SMO (0.43) | LMNAMEN1KMT2ASMOMAPT | |
| SCHEMBL22323205 | 0.88 | SMO (0.39) | SMO | |
| SCHEMBL24361008 | 0.85 | SMO (0.39) | SMO | |
| SCHEMBL19968856 | 0.84 | PTPN11 (0.35) | SMO | |
| SCHEMBL29464413 | 0.84 | PTPN11 (0.35) | SMO | |
| SCHEMBL23748043 | 0.84 | SMO (0.36) | KMT2ASMN1; SMN2SMOL3MBTL1ALDH1A1 | |
| SCHEMBL29464492 | 0.84 | SMO (0.34) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |