Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 3/20 | 0.35 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.34 |
| ▸ | WDR5 | P61964 | 2/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925197 | 1.00 | GHSR (0.39) | GHSRHSD11B1MLNRSCN1ASCN8A | |
| SCHEMBL19927776 | 1.00 | GHSR (0.39) | GHSRHSD11B1MLNRSCN1ASCN8A | |
| SCHEMBL19925195 | 1.00 | GHSR (0.39) | GHSRHSD11B1MLNRSCN1ASCN8A | |
| SCHEMBL29464302 | 1.00 | GHSR (0.39) | GHSRHSD11B1MLNRSCN1ASCN8A | |
| Hydrochloric Acid SCHEMBL29464932 | 0.99 | GHSR (0.38) | GHSRHSD11B1MLNRSCN1ASCN8A | |
| Hydrochloric Acid SCHEMBL19925626 | 0.99 | GHSR (0.38) | GHSRHSD11B1MLNRSCN1ASCN8A | |
| Hydrochloric Acid SCHEMBL29464872 | 0.99 | GHSR (0.38) | GHSRHSD11B1MLNRSCN1ASCN8A | |
| Hydrochloric Acid SCHEMBL19925628 | 0.99 | GHSR (0.38) | GHSRHSD11B1MLNRSCN1ASCN8A | |
| Hydrochloric Acid SCHEMBL19951317 | 0.99 | GHSR (0.38) | GHSRHSD11B1MLNRSCN1ASCN8A | |
| SCHEMBL29464321 | 0.91 | GHSR (0.47) | GHSRSCN1ASCN8AWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |