Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 17/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19927741 | 1.00 | SCN9A (0.49) | SCN9AALDH1A1LMNAGLAL3MBTL1 | |
| SCHEMBL29464315 | 0.87 | SLC22A12 (0.40) | SCN9A | |
| SCHEMBL19925093 | 0.87 | SLC22A12 (0.40) | SCN9A | |
| SCHEMBL29464473 | 0.84 | SCN9A (0.44) | SCN9AALDH1A1LMNAHSD11B1 | |
| SCHEMBL19925056 | 0.84 | SCN9A (0.44) | SCN9AALDH1A1LMNAHSD11B1 | |
| SCHEMBL19951268 | 0.83 | SCN9A (0.45) | SCN9AHSD11B1 | |
| SCHEMBL29464404 | 0.83 | LMNA (0.41) | SCN9AALDH1A1LMNAGLAL3MBTL1 | |
| SCHEMBL19927812 | 0.83 | LMNA (0.41) | SCN9AALDH1A1LMNAGLAL3MBTL1 | |
| SCHEMBL19927808 | 0.82 | SCN9A (0.41) | SCN9AALDH1A1LMNA | |
| SCHEMBL29464553 | 0.82 | SCN9A (0.41) | SCN9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |