Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | SCN1A | P35498 | 2/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | RORB | Q92753 | 1/20 | 0.31 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29464305 | 1.00 | SCN9A (0.32) | SCN9AEIF2AK4BTKSCN1ASCN8A | |
| SCHEMBL19927721 | 1.00 | SCN9A (0.32) | SCN9AEIF2AK4BTKSCN1ASCN8A | |
| SCHEMBL29464531 | 1.00 | SCN9A (0.32) | SCN9AEIF2AK4BTKSCN1ASCN8A | |
| SCHEMBL19951413 | 1.00 | SCN9A (0.32) | SCN9AEIF2AK4BTKSCN1ASCN8A | |
| SCHEMBL19951451 | 1.00 | SCN9A (0.32) | SCN9AEIF2AK4BTKSCN1ASCN8A | |
| SCHEMBL19925421 | 0.95 | SCN9A (0.33) | SCN9AEIF2AK4BTKSCN1ASCN8A | |
| SCHEMBL19951401 | 0.95 | SCN9A (0.33) | SCN9AEIF2AK4BTKSCN1ASCN8A | |
| SCHEMBL19925420 | 0.94 | SCN9A (0.33) | SCN9AEIF2AK4BTKSCN1ASCN8A | |
| SCHEMBL19925426 | 0.93 | EPHX2 (0.34) | SCN9AEIF2AK4BTKSCN1ASCN8A | |
| SCHEMBL19951366 | 0.91 | RORC (0.33) | SCN9ASCN1ASCN8ARORCKIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |