Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.38 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 2/20 | 0.37 |
| ▸ | SKP1 | P63208 | 2/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.37 |
| ▸ | STS | P08842 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19925728 | 1.00 | MCL1 (0.42) | MCL1GPR119RAF1BRAFBRD4 | |
| SCHEMBL29464405 | 0.91 | BRD4 (0.41) | BRD4MEN1KMT2ASUV39H2KIF18A | |
| SCHEMBL19925051 | 0.91 | BRD4 (0.41) | BRD4MEN1KMT2ASUV39H2KIF18A | |
| SCHEMBL23748047 | 0.91 | TRPV1 (0.38) | MCL1RAF1BRAFKMT2AMAPT | |
| SCHEMBL19925164 | 0.86 | STS (0.41) | GPR119BRD4TGFBR1MEN1KMT2A | |
| SCHEMBL29464463 | 0.86 | STS (0.41) | GPR119BRD4TGFBR1MEN1KMT2A | |
| SCHEMBL19968832 | 0.85 | IDH1 (0.37) | MCL1RAF1BRAFMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL19951419 | 0.85 | IDH1 (0.37) | MCL1RAF1BRAFMEN1KMT2A | |
| SCHEMBL23770751 | 0.84 | GPR119 (0.40) | MCL1GPR119RAF1BRAFMEN1 | |
| SCHEMBL19925386 | 0.84 | RAF1 (0.37) | MCL1RAF1BRAFKMT2ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |