Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | KIF18A | Q8NI77 | 4/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | GALR2 | O43603 | 1/20 | 0.31 |
| ▸ | GALR1 | P47211 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29464935 | 1.00 | KMO (0.33) | KMORORCSCN9AEIF2AK4BTK | |
| SCHEMBL19927744 | 1.00 | KMO (0.33) | KMORORCSCN9AEIF2AK4BTK | |
| SCHEMBL19951410 | 1.00 | KMO (0.33) | KMORORCSCN9AEIF2AK4BTK | |
| SCHEMBL29464931 | 1.00 | KMO (0.33) | KMORORCSCN9AEIF2AK4BTK | |
| SCHEMBL19925137 | 1.00 | KMO (0.33) | KMORORCSCN9AEIF2AK4BTK | |
| SCHEMBL19927756 | 0.91 | SCN9A (0.33) | RORCSCN9AEIF2AK4BTKKIF18A | |
| SCHEMBL29464399 | 0.91 | SCN9A (0.33) | RORCSCN9AEIF2AK4BTKKIF18A | |
| SCHEMBL29464499 | 0.91 | SCN9A (0.33) | RORCSCN9AEIF2AK4BTKKIF18A | |
| SCHEMBL29464304 | 0.91 | SCN9A (0.33) | RORCSCN9AEIF2AK4BTKKIF18A | |
| SCHEMBL19951386 | 0.91 | SCN9A (0.33) | RORCSCN9AEIF2AK4BTKKIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |