Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RBP4 | P02753 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 9/20 | 0.44 |
| ▸ | PRKCA | P17252 | 7/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615998 | 0.75 | KMT2A (0.65) | KMT2APRKCQPRKCAPRKCDMYC | |
| SCHEMBL3532211 | 0.73 | OPRK1 (0.60) | KMT2ACHIAPRKCQOPRK1 | |
| SCHEMBL2418788 | 0.72 | EPHX2 (0.55) | RBP4PRKCQPRKCAPRKCDTSHR | |
| SCHEMBL16034182 | 0.71 | KMT2A (0.68) | KMT2ARBP4TTRMYCTSHR | |
| SCHEMBL24297726 | 0.71 | KMT2A (0.68) | KMT2ARBP4TTRMYCTSHR | |
| SCHEMBL27989986 | 0.70 | KMT2A (0.61) | KMT2ACHIAPRKCQTSHRHSD17B10 | |
| SCHEMBL4109672 | 0.70 | OPRK1 (0.48) | TSHRHSD17B10OPRK1 | |
| SCHEMBL1264645 | 0.70 | KMT2A (0.66) | KMT2ARBP4TTRMYCOPRK1 | |
| SCHEMBL22717519 | 0.70 | KMT2A (0.62) | KMT2ARBP4TTRCHIAMYC | |
| SCHEMBL30686213 | 0.70 | KMT2A (0.55) | KMT2ARBP4TTRCHIAPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-B | N- (pyridin-2-yl) pyridine-sulfonamide derivatives and their use for the treatment of disease | 诺华股份有限公司 | 2022-03-18 | — | — | CN | disclosed |