Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20519313 | 0.77 | NPC1 (0.43) | CYP4F2CYP4A11MCL1KDM5BRXRA | |
| SCHEMBL20524397 | 0.77 | NPC1 (0.43) | CYP4F2CYP4A11MCL1KDM5BRXRA | |
| SCHEMBL17714250 | 0.76 | CYP4F2 (0.43) | CYP4F2CYP4A11MCL1KDM5BFLT3 | |
| SCHEMBL21334944 | 0.75 | KDM5B (0.37) | CYP4F2CYP4A11MCL1KDM5BFLT3 | |
| SCHEMBL31180437 | 0.75 | KDM5B (0.38) | CYP4F2CYP4A11MCL1KDM5BFLT3 | |
| SCHEMBL1144773 | 0.75 | LMNA (0.41) | CYP4F2CYP4A11MCL1KDM5BFLT3 | |
| SCHEMBL17021769 | 0.75 | KDM5B (0.36) | CYP4F2CYP4A11MCL1KDM5BFLT3 | |
| SCHEMBL17018590 | 0.75 | KDM5B (0.36) | CYP4F2CYP4A11MCL1KDM5BFLT3 | |
| SCHEMBL21334896 | 0.73 | NPC1 (0.49) | CYP4F2CYP4A11KDM5B | |
| SCHEMBL21412335 | 0.72 | KDM5B (0.43) | CYP4F2CYP4A11MCL1KDM5BFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114245794-A | Compounds for the treatment of huntington's disease | PTC医疗公司 | 2022-03-25 | — | — | CN | disclosed |