SCHEMBL29465735

SCHEMBL29465735

CC(C)(C)OC(=O)NC(CC=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CTSK P43235 6/20 0.52
CTSS P25774 3/20 0.52
MAPT P10636 1/20 0.52
ATM Q13315 1/20 0.49
CTSL P07711 1/20 0.44
CTSB P07858 1/20 0.44
GABRB1 P18505 1/20 0.44
GABRB2 P47870 1/20 0.44
PPARA Q07869 2/20 0.43
PPARG P37231 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717324 1.00 CTSK (0.52) CTSKCTSSMAPTATMCTSL
SCHEMBL1784108 1.00 CTSK (0.52) CTSKCTSSMAPTATMCTSL
SCHEMBL5460811 1.00 CTSK (0.52) CTSKCTSSMAPTATMCTSL
SCHEMBL14168735 0.89 CTSK (0.50) CTSKCTSSMAPTATMCTSL
SCHEMBL29952714 0.86 PPARG (0.44) CTSKCTSSMAPTATMPPARA
SCHEMBL29955950 0.86 PPARG (0.44) CTSKCTSSMAPTATMPPARA
SCHEMBL3372679 0.86 AAK1 (0.43) CTSKCTSSMAPTATM
SCHEMBL14436617 0.86 CTSK (0.50) CTSKCTSSMAPTATMCTSL
SCHEMBL3378239 0.86 CTSK (0.46) CTSKCTSSMAPTATM
SCHEMBL27674504 0.86 CTSK (0.46) CTSKCTSSMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-110845369-B Synthetic method of dapoxetine and intermediate thereof 浙江工业大学 2022-03-18 CN disclosed