Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25312272 | 0.84 | LANCL2 (0.69) | LANCL2SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL29484641 | 0.83 | LANCL2 (0.55) | LANCL2SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL25311481 | 0.81 | LANCL2 (0.58) | LANCL2SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL25310879 | 0.79 | LANCL2 (0.61) | LANCL2SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL25311732 | 0.78 | LANCL2 (0.57) | LANCL2SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL29466263 | 0.78 | LANCL2 (0.44) | LANCL2SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL25263046 | 0.77 | LANCL2 (0.56) | LANCL2SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL29484631 | 0.76 | LANCL2 (0.59) | LANCL2SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL25878688 | 0.76 | LANCL2 (0.59) | LANCL2SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL25312882 | 0.76 | LANCL2 (0.69) | LANCL2SMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195780-A | Carbonyl heterocyclic compound and application thereof | 上海医药集团股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195806-A | Carbonyl heterocyclic compound and application thereof | 上海医药集团股份有限公司 | 2022-03-18 | — | — | CN | disclosed |