Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28716146 | 1.00 | GAA (0.50) | GAAKDM4DEPHX2NFKB1NFKB2 | |
| SCHEMBL17321204 | 1.00 | GAA (0.50) | GAAKDM4DEPHX2NFKB1NFKB2 | |
| SCHEMBL30035060 | 1.00 | GAA (0.50) | GAAKDM4DEPHX2NFKB1NFKB2 | |
| SCHEMBL20050036 | 0.90 | GAA (0.49) | GAAKDM4DEPHX2NFKB1NFKB2 | |
| SCHEMBL17321201 | 0.90 | GAA (0.49) | GAAKDM4DEPHX2NFKB1NFKB2 | |
| SCHEMBL15964827 | 0.85 | GAA (0.48) | GAAKDM4DEPHX2NFKB1NFKB2 | |
| SCHEMBL18419874 | 0.85 | GAA (0.53) | GAAEPHX2NFKB1NFKB2RELA | |
| SCHEMBL17321197 | 0.85 | GAA (0.53) | GAAEPHX2NFKB1NFKB2RELA | |
| SCHEMBL19641523 | 0.83 | RIPK1 (0.39) | RIPK1 | |
| SCHEMBL20045151 | 0.83 | GAA (0.50) | GAAKDM4DEPHX2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206861-A | Fused heteroaryl compounds useful as RIPK1 inhibitors | 比西切姆有限公司 | 2022-03-18 | — | — | CN | disclosed |