SCHEMBL29467205

SCHEMBL29467205

COc1ccc(/C(C)=N\O)cc1OC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
POLB P06746 1/20 0.64
GAA P10253 4/20 0.61
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
CYP2C9 P11712 2/20 0.57
CYP2C19 P33261 2/20 0.57
TSHR P16473 2/20 0.57
CYP1A2 P05177 1/20 0.57
CYP3A4 P08684 1/20 0.57
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA7 P43166 1/20 0.55
TPMT P51580 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4864755 1.00 MAPT (0.64) MAPTSMN1; SMN2POLBGAAMEN1
SCHEMBL12585063 0.85 ALOX15 (0.50) MAPTSMN1; SMN2POLBGAAMEN1
SCHEMBL13268873 0.85 GAA (0.63) MAPTPOLBGAAMEN1KMT2A
SCHEMBL17548941 0.85 GAA (0.63) MAPTPOLBGAAMEN1KMT2A
SCHEMBL14632560 0.83 MAPT (0.46) MAPTSMN1; SMN2POLBGAAMEN1
SCHEMBL14632561 0.83 MAPT (0.46) MAPTSMN1; SMN2POLBGAAMEN1
SCHEMBL13837780 0.83 MAPT (0.46) MAPTSMN1; SMN2POLBGAAMEN1
SCHEMBL4159465 0.82 CYP2C9 (0.55) MAPTSMN1; SMN2POLBGAAMEN1
SCHEMBL7330114 0.82 SMPD1 (0.54) MAPTSMN1; SMN2POLBGAAMEN1
SCHEMBL7322765 0.81 PDE4D (0.70) PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12083494-B2 Modified clay sorbents and methods of sorbing PFAS using the same SPECIALTY MINERALS (MICHIGAN) INC. (US) 2024-09-10 US disclosed
US-20220339600-A1 MODIFIED CLAY SORBENTS AND METHODS OF SORBING PFAS USING THE SAME AMCOL INTERNATIONAL CORPORATION 2022-10-27 US disclosed
EP-3972732-A1 MODIFIED CLAY SORBENTS AND METHODS OF SORBING PFAS USING THE SAME Specialty Minerals (Michigan) Inc. (US) 2022-03-30 EP disclosed