Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 16/20 | 0.74 |
| ▸ | ADRA2B | P18089 | 14/20 | 0.74 |
| ▸ | ADRA2C | P18825 | 14/20 | 0.74 |
| ▸ | ADRA1B | P35368 | 14/20 | 0.74 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18826068 | 1.00 | ADRA2A (0.74) | ADRA2AADRA2BADRA2CADRA1BIDO1 | |
| Fipamezole SCHEMBL18826053 | 0.85 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1BIDO1 | |
| SCHEMBL18826067 | 0.85 | ADRA2A (0.72) | ADRA2AADRA2BADRA2CADRA1BIDO1 | |
| Atipamezole SCHEMBL304971 | 0.84 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1B | |
| Atipamezole SCHEMBL29357620 | 0.84 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CADRA1B | |
| Fipamezole SCHEMBL29489936 | 0.84 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1BIDO1 | |
| Atipamezole SCHEMBL30249868 | 0.82 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1B | |
| Atipamezole SCHEMBL203964 | 0.82 | ADRA2A (0.97) | ADRA2AADRA2BADRA2CADRA1B | |
| SCHEMBL18826072 | 0.81 | ADRA2A (0.75) | ADRA2AADRA2BADRA2CADRA1B | |
| SCHEMBL18826074 | 0.81 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CADRA1BIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2022009155-A | LOCAL AND REGIONAL ANESTHESIA AND ANALGESIA | ユニバーシティー オブ ルイヴィル リサーチ ファウンデーション，インコーポレーテッド | 2022-01-14 | — | — | JP | disclosed |