Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.49 |
| ▸ | NMT1 | P30419 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL121016 | 1.00 | AKR1B1 (0.49) | AKR1B1NMT1DGAT1TRPV4FLT1 | |
| SCHEMBL1790226 | 0.83 | FLT1 (0.39) | AKR1B1NMT1DGAT1TRPV4FLT1 | |
| SCHEMBL15845179 | 0.81 | AKR1B1 (0.50) | AKR1B1NMT1DGAT1FLT1FLT4 | |
| SCHEMBL28144564 | 0.81 | AKR1B1 (0.50) | AKR1B1NMT1DGAT1FLT1FLT4 | |
| SCHEMBL29430705 | 0.79 | NMT1 (0.49) | AKR1B1NMT1DGAT1APLNRHSD11B1 | |
| SCHEMBL1581645 | 0.79 | NMT1 (0.49) | AKR1B1NMT1DGAT1APLNRHSD11B1 | |
| SCHEMBL15594384 | 0.79 | AKR1B1 (0.49) | AKR1B1NMT1DGAT1FLT1FLT4 | |
| SCHEMBL10296145 | 0.79 | AKR1B1 (0.49) | AKR1B1NMT1DGAT1FLT1FLT4 | |
| SCHEMBL30714290 | 0.79 | AKR1B1 (0.49) | AKR1B1NMT1DGAT1APLNR | |
| SCHEMBL1347919 | 0.79 | AKR1B1 (0.49) | AKR1B1NMT1DGAT1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025136671-A1 | ANILINO-PYRAZOLE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| EP-4540230-A1 | ANILINO-PYRAZOLE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | Ensem Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244710-A1 | ANILINO-PYRAZOLE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| WO-2022051286-A1 | N-LINKED GLYCOSYLATION INHIBITORS AND METHODS OF USING SAME | YALE UNIVERSITY (US) | 2022-03-10 | — | — | WO | disclosed |