Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.49 |
| ▸ | CCR2 | P41597 | 3/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581645 | 1.00 | NMT1 (0.49) | NMT1AKR1B1CCR2DGAT1APLNR | |
| SCHEMBL707997 | 0.83 | WDR5 (0.42) | NMT1AKR1B1CCR2DGAT1APLNR | |
| SCHEMBL15845179 | 0.81 | AKR1B1 (0.50) | NMT1AKR1B1DGAT1APLNRALOX15 | |
| SCHEMBL28144564 | 0.81 | AKR1B1 (0.50) | NMT1AKR1B1DGAT1APLNRALOX15 | |
| SCHEMBL3112984 | 0.80 | CCR2 (0.44) | CCR2TSHRL3MBTL1CA1CA2 | |
| SCHEMBL16011120 | 0.80 | NMT1 (0.47) | NMT1AKR1B1DGAT1APLNRALOX15 | |
| SCHEMBL1347919 | 0.79 | AKR1B1 (0.49) | NMT1AKR1B1DGAT1APLNRCA1 | |
| SCHEMBL10296145 | 0.79 | AKR1B1 (0.49) | NMT1AKR1B1DGAT1APLNRALOX15 | |
| SCHEMBL15594384 | 0.79 | AKR1B1 (0.49) | NMT1AKR1B1DGAT1APLNRALOX15 | |
| SCHEMBL30714290 | 0.79 | AKR1B1 (0.49) | NMT1AKR1B1DGAT1APLNRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306646-A | Process for preparing pyrrole amide compounds and intermediates therefor | 广东东阳光药业股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119306645-A | Process for preparing pyrrole amide compounds and intermediates therefor | 广东东阳光药业股份有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-115246785-B | Process for preparing pyrrole amide compounds | 年衍药业(珠海)有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115246785-A | Process for producing pyrrole amide compound | 年衍药业(珠海)有限公司 | 2022-10-28 | — | — | CN | disclosed |
| EP-3966196-A1 | PHENYL-SULFAMOYL.BENZOYC ACIDS AS ERAP1 MODULATORS | Grey Wolf Therapeutics Limited (GB) | 2022-03-16 | — | — | EP | disclosed |