Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26983354 | 1.00 | PRNP (0.39) | PRNPMCOLN2ATMPOLBLMNA | |
| SCHEMBL23203470 | 0.76 | MAPT (0.43) | POLBLMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL29467295 | 0.74 | ATM (0.57) | PRNPATMPOLBLMNATP53 | |
| SCHEMBL25272535 | 0.74 | L3MBTL1 (0.53) | PRNPATMPOLBLMNATP53 | |
| SCHEMBL26983367 | 0.74 | ATM (0.57) | PRNPATMPOLBLMNATP53 | |
| SCHEMBL30466301 | 0.71 | HSD17B10 (0.43) | PRNPLMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL25235066 | 0.71 | HSD17B10 (0.43) | PRNPLMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL4517751 | 0.71 | SMN1; SMN2 (0.40) | GAAHTTSMN1; SMN2MAPTCA12 | |
| SCHEMBL2113235 | 0.68 | MAPT (0.60) | POLBLMNATP53GAAHTT | |
| SCHEMBL1369047 | 0.68 | MAPT (0.56) | POLBLMNATP53GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022051286-A1 | N-LINKED GLYCOSYLATION INHIBITORS AND METHODS OF USING SAME | YALE UNIVERSITY (US) | 2022-03-10 | — | — | WO | disclosed |