Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972879 | 1.00 | LMNA (0.46) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL11551245 | 1.00 | LMNA (0.46) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL11551248 | 1.00 | LMNA (0.46) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL10974534 | 0.88 | LMNA (0.45) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL10974538 | 0.88 | LMNA (0.45) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL296125 | 0.87 | LMNA (0.34) | LMNA | |
| SCHEMBL10988592 | 0.85 | LMNA (0.43) | LMNAALDH1A1TP53MAPTMEN1 | |
| SCHEMBL11147386 | 0.83 | LMNA (0.46) | LMNAALDH1A1TP53TSHRHTT | |
| SCHEMBL295631 | 0.82 | POLA1 (0.32) | HTT | |
| SCHEMBL296460 | 0.82 | TSHR (0.33) | LMNAALDH1A1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4681953-A | Process for preparing dihalovinylcyclopropanecarboxylates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-07-21 | — | — | US | claimed |
| EP-1792889-B1 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL CO (JP) | 2015-03-04 | — | — | EP | disclosed |
| EP-1547995-B1 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL CO (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-1683783-B1 | Chiral copper complex and production processes thereof and using the same | SUMITOMO CHEMICAL CO (JP) | 2012-03-14 | — | — | EP | disclosed |
| EP-1683782-B1 | Chiral copper complex and production processes thereof and using the same | SUMITOMO CHEMICAL CO (JP) | 2012-03-14 | — | — | EP | disclosed |
| US-7741511-B2 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-22 | — | — | US | disclosed |
| US-7399873-B2 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-07-15 | — | — | US | disclosed |
| EP-1120402-B1 | Chiral copper complex and production processes thereof and using the same | SUMITOMO CHEMICAL CO (JP) | 2008-06-25 | — | — | EP | disclosed |
| US-20080033194-A1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS | SOUDA HIROSHI | 2008-02-07 | — | — | US | disclosed |
| US-20080009648-A1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS | SOUDA HIROSHI | 2008-01-10 | — | — | US | disclosed |
| US-4552972-A | Chiral copper complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-11-12 | — | — | US | disclosed |
| US-4532258-A | Controlling insects, mites, pests | KURARAY CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |
| EP-0128012-A2 | Novel chiral copper complex and asymmetric synthesis of cyclopropanecarboxylate derivatives using said complex as catalyst | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-12 | — | — | EP | disclosed |
| US-4454343-A | Intermediates in a process for preparing dihalovinylcyclopropanecarboxylates | FMC CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| EP-0022608-B1 | PROCESS FOR THE PREPARATION OF CYCLOPROPANE CARBOXYLIC ACID ESTERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-07-06 | — | — | EP | disclosed |
| US-4350811-A | Chiral sugar complexes | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| EP-0003683-B1 | PROCESS FOR PREPARING HIGH CIS 3-(2,2,2-TRICHLOROETHYL)-2,2-DIMETHYLCYCLOPROPANE-1-CARBOXYLATES | FMC Corporation (US) | 1982-09-15 | — | — | EP | disclosed |
| EP-0024797-A1 | Chiral sugar complexes and process for their preparation | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-03-11 | — | — | EP | disclosed |
| US-4214097-A | Process for preparing dihalovinylcyclopropanecarboxylates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1980-07-22 | — | — | US | disclosed |
| US-4166064-A | 4,6,6,6 -TETRACHLORO-3,3-DIMETHYLHEXANOATE, ALKALI METAL TERT-ALKOXIDE | FMC CORPORATION (US) | 1979-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033194-A1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS | ACSL6, ALKBH3, ACSL1 | LMNA 3667/4885ALDH1A1 184/4885TP53 3860/4885 |
| US-20080009648-A1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS | ACSL6, ALKBH3, ACSL1 | LMNA 3667/4885ALDH1A1 184/4885TP53 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.