Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18073542 | 1.00 | CALM1 (0.44) | CALM1CAMKK2TSHRMAPK1MEN1 | |
| SCHEMBL15357270 | 1.00 | CALM1 (0.44) | CALM1CAMKK2TSHRMAPK1MEN1 | |
| SCHEMBL24178220 | 0.96 | CALM1 (0.44) | CALM1CAMKK2TSHRMAPK1MEN1 | |
| SCHEMBL21043434 | 0.96 | CALM1 (0.44) | CALM1CAMKK2TSHRMAPK1MEN1 | |
| SCHEMBL12918861 | 0.91 | TSHR (0.45) | CALM1CAMKK2TSHRALDH1A1GAA | |
| SCHEMBL24178228 | 0.90 | CALM1 (0.42) | CALM1CAMKK2TSHRMAPK1MEN1 | |
| SCHEMBL26147215 | 0.89 | CALM1 (0.40) | CALM1CAMKK2TSHRMAPK1MEN1 | |
| SCHEMBL8281044 | 0.89 | MEN1 (0.51) | CALM1CAMKK2TSHRMAPK1MEN1 | |
| SCHEMBL10138451 | 0.86 | TSHR (0.47) | CALM1CAMKK2TSHRMAPK1ALDH1A1 | |
| SCHEMBL14870667 | 0.86 | TSHR (0.47) | CALM1CAMKK2TSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426727-A2 | SPECIFIC CONJUGATION OF AN ANTIBODY | Hangzhou Dac Biotech Co., Ltd. (CN) | 2024-09-11 | — | — | EP | disclosed |
| WO-2022078524-A4 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022078524-A2 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |