SCHEMBL29467645

SCHEMBL29467645

COCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CC[C@H](N)C(=O)NCCCC(=O)OC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PLK1 P53350 1/20 0.45
▸ TLR2 O60603 12/20 0.38
▸ TSHR P16473 1/20 0.38
▸ GLP1R P43220 3/20 0.36
▸ CAPN1 P07384 1/20 0.36
▸ DPP7 Q9UHL4 1/20 0.36
▸ LTA4H P09960 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29131983 0.90 PLK1 (0.42) PLK1TLR2DPP7
SCHEMBL26232048 0.90 PLK1 (0.42) PLK1TLR2DPP7
SCHEMBL31756841 0.90 PLK1 (0.42) PLK1TLR2DPP7
SCHEMBL23451329 0.87 DPP7 (0.40) PLK1TLR2TSHRGLP1RDPP7
SCHEMBL29467697 0.87 DPP7 (0.40) PLK1TLR2TSHRGLP1RDPP7
SCHEMBL23451330 0.87 DPP7 (0.40) PLK1TLR2TSHRGLP1RDPP7
SCHEMBL29548342 0.86 MEN1 (0.40) PLK1TLR2TSHRCAPN1
SCHEMBL25708285 0.86 MEN1 (0.46) TLR2TSHRGLP1RDPP7LTA4H
SCHEMBL19447825 0.82 PLK1 (0.39) PLK1TSHRDPP7LTA4H
SCHEMBL30748709 0.82 TSHR (0.53) TLR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4426727-A2 SPECIFIC CONJUGATION OF AN ANTIBODY Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
WO-2022078524-A4 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-12-08 — — WO disclosed
WO-2022078524-A2 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-04-21 — — WO disclosed
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