Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29131983 | 0.92 | PLK1 (0.42) | PLK1DPP7MEN1KMT2A | |
| SCHEMBL31756841 | 0.92 | PLK1 (0.42) | PLK1DPP7MEN1KMT2A | |
| SCHEMBL26232048 | 0.92 | PLK1 (0.42) | PLK1DPP7MEN1KMT2A | |
| SCHEMBL16757624 | 0.84 | MEN1 (0.43) | PLK1DPP7MEN1KMT2AGAA | |
| SCHEMBL16757623 | 0.84 | MEN1 (0.43) | PLK1DPP7MEN1KMT2AGAA | |
| SCHEMBL23417972 | 0.84 | TLR2 (0.44) | PLK1DPP7RRM1GNAI3GNAO1 | |
| SCHEMBL16791114 | 0.84 | PLK1 (0.42) | PLK1DPP7RRM1GNAI3GNAO1 | |
| SCHEMBL23451305 | 0.83 | DPP7 (0.49) | PLK1DPP7RRM1GNAI3GNAO1 | |
| SCHEMBL23451304 | 0.83 | DPP7 (0.49) | PLK1DPP7RRM1GNAI3GNAO1 | |
| SCHEMBL21836141 | 0.83 | TLR2 (0.45) | PLK1DPP7MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464379-B1 | ANTIBODIES, USES THEREOF AND CONJUGATES THEREOF | ABZENA UK LTD (GB) | 2023-09-27 | — | — | EP | disclosed |
| US-11485792-B2 | Antibodies, uses thereof and conjugates thereof | POLYTHERICS LIMITED | 2022-11-01 | — | — | US | disclosed |
| US-20190144562-A1 | ANTIBODIES, USES THEREOF AND CONJUGATES THEREOF | ABZENA (UK) LIMITED (GB) | 2019-05-16 | — | — | US | disclosed |
| US-20170304461-A1 | Process For The Conjugation Of A Peptide Or Protein With A Reagent Comprising A Leaving Group Including A Portion Of PEG | POLYTHERICS LIMITED (GB) | 2017-10-26 | — | — | US | disclosed |
| US-20170290925-A1 | Conjugates And Conjugating Reagents | POLYTHERICS LIMITED (GB) | 2017-10-12 | — | — | US | disclosed |
| US-20170290925-A1 | Conjugates And Conjugating Reagents | POLYTHERICS LIMITED (GB) | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170304461-A1 | Process For The Conjugation Of A Peptide Or Protein With A Reagent Comprising A Leaving Group Including A Portion Of PEG | LNPEP, ANPEP, NGLY1 | PLK1 1836/4885DPP7 2003/4885RRM1 3363/4885 |
| US-20170290925-A1 | Conjugates And Conjugating Reagents | ANPEP, NGLY1, PCTP | PLK1 2652/4885DPP7 2895/4885RRM1 2147/4885 |
| US-20190144562-A1 | ANTIBODIES, USES THEREOF AND CONJUGATES THEREOF | KLK3, VSIG8, IGLV6-57 | PLK1 505/4885DPP7 1474/4885RRM1 4231/4885 |
| US-11485792-B2 | Antibodies, uses thereof and conjugates thereof | KLK3, VSIG8, IGLV6-57 | PLK1 505/4885DPP7 1474/4885RRM1 4231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.