SCHEMBL29467657

SCHEMBL29467657

O=C(O)CCOCCOCCOCCOCCNC(=O)CCOCCOCCOCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCC(=O)OCc1ccccc1)C(=O)OCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 1/20 0.44
EPOR P19235 3/20 0.44
GLP1R P43220 8/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
BCHE P06276 1/20 0.42
ACHE P22303 1/20 0.42
FOLH1 Q04609 2/20 0.42
GLO1 Q04760 1/20 0.42
SIRT2 Q8IXJ6 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30266832 1.00 MEN1 (0.44) MEN1ALDH1A1HPGDKMT2AEPOR
SCHEMBL19049880 0.93 GLP1R (0.51) MEN1ALDH1A1HPGDKMT2AEPOR
SCHEMBL20597795 0.93 GLP1R (0.51) MEN1ALDH1A1HPGDKMT2AEPOR
SCHEMBL19031554 0.91 GLP1R (0.53) MEN1ALDH1A1HPGDKMT2AEPOR
SCHEMBL20597880 0.91 GLP1R (0.53) MEN1ALDH1A1HPGDKMT2AEPOR
SCHEMBL29467621 0.90 TLR2 (0.44) MEN1ALDH1A1HPGDKMT2AGLP1R
SCHEMBL25332437 0.89 LMNA (0.53) MEN1KMT2AEPORLMNASMN1; SMN2
SCHEMBL29467600 0.89 LMNA (0.53) MEN1KMT2AEPORLMNASMN1; SMN2
SCHEMBL28928287 0.88 LMNA (0.54) MEN1KMT2AEPORLMNASMN1; SMN2
SCHEMBL19025481 0.88 GLP1R (0.46) MEN1ALDH1A1HPGDKMT2AEPOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4426727-A2 SPECIFIC CONJUGATION OF AN ANTIBODY Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 EP disclosed
WO-2022078524-A4 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-12-08 WO disclosed
EP-3986463-A1 A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS Hangzhou Dac Biotech Co., Ltd. (CN) 2022-04-27 EP disclosed
WO-2022078524-A2 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-04-21 WO disclosed