Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1130974 | 1.00 | KMT2A (0.58) | KMT2AMEN1HTTTP53MAPT | |
| SCHEMBL3278521 | 0.94 | MEN1 (0.53) | KMT2AMEN1HTTTP53MAPT | |
| SCHEMBL27947180 | 0.92 | KMT2A (0.52) | KMT2AMEN1HTTTP53MAPT | |
| Dinitrophenylene SCHEMBL27868275 | 0.90 | MEN1 (0.59) | KMT2AMEN1HTTTP53MAPT | |
| SCHEMBL1242359 | 0.89 | MEN1 (0.59) | KMT2AMEN1HTTTP53MAPT | |
| SCHEMBL15228420 | 0.86 | TSHR (0.52) | KMT2AMEN1HTTTP53MAPT | |
| SCHEMBL10909455 | 0.86 | TSHR (0.52) | KMT2AMEN1HTTTP53MAPT | |
| SCHEMBL12760705 | 0.86 | NFE2L2 (0.60) | KMT2AMEN1HTTTP53MAPT | |
| SCHEMBL12760706 | 0.86 | NFE2L2 (0.60) | KMT2AMEN1HTTTP53MAPT | |
| SCHEMBL9190260 | 0.85 | TSHR (0.50) | KMT2AMEN1HTTTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114324620-B | Method for detecting p-trifluoromethoxy aniline and related impurities | 鲁南制药集团股份有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-114324620-B | Method for detecting p-trifluoromethoxy aniline and related impurities | 鲁南制药集团股份有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-118146102-A | Method for synthesizing diaryl amine or triarylamine by using nitroaromatic hydrocarbon as raw material | 广西大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |
| EP-4277901-A1 | ISOINDOLINONE COMPOUNDS | Monte Rosa Therapeutics, Inc. (US) | 2023-11-22 | — | — | EP | disclosed |
| EP-4278014-A1 | TREATMENT OF MYC-DRIVEN CANCERS WITH GSPT1 DEGRADERS | Monte Rosa Therapeutics, Inc. (US) | 2023-11-22 | — | — | EP | disclosed |
| CN-113105475-B | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2022-09-09 | — | — | CN | disclosed |
| WO-2022152822-A1 | TREATMENT OF MYC-DRIVEN CANCERS WITH GSPT1 DEGRADERS | MONTE ROSA THERAPEUTICS AG (CH) | 2022-07-21 | — | — | WO | disclosed |
| WO-2022152821-A1 | ISOINDOLINONE COMPOUNDS | MONTE ROSA THERAPEUTICS AG (CH) | 2022-07-21 | — | — | WO | disclosed |
| CN-114324620-A | Method for detecting p-trifluoromethoxyaniline and related impurities | 鲁南制药集团股份有限公司 | 2022-04-12 | — | — | CN | disclosed |