Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 19/20 | 1.00 |
| ▸ | FDPS | P14324 | 5/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17208162 | 0.81 | GGPS1 (1.00) | GGPS1FDPS | |
| SCHEMBL11844372 | 0.78 | GGPS1 (0.64) | GGPS1FDPS | |
| SCHEMBL29469324 | 0.78 | GGPS1 (1.00) | GGPS1FDPS | |
| SCHEMBL29469326 | 0.76 | GGPS1 (0.85) | GGPS1FDPS | |
| SCHEMBL20424028 | 0.76 | GGPS1 (0.76) | GGPS1FDPS | |
| SCHEMBL11845658 | 0.73 | GGPS1 (0.57) | GGPS1 | |
| SCHEMBL20430344 | 0.72 | GGPS1 (0.61) | GGPS1FDPS | |
| SCHEMBL11848221 | 0.72 | GGPS1 (0.56) | GGPS1FDPS | |
| SCHEMBL11841550 | 0.71 | GGPS1 (0.55) | GGPS1 | |
| SCHEMBL11844573 | 0.71 | GGPS1 (0.54) | GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573992-B1 | SUBSTITUTED BICYCLIC PYRIMIDINE-BASED COMPOUNDS AND COMPOSITIONS AND USES THEREOF | TSANTRIZOS YOULA S (CA) | 2022-04-13 | — | — | EP | disclosed |
| US-11279719-B2 | Substituted bicyclic pyrimidine-based compounds and compositions and uses thereof | Tsantrizos, Youla S. (CA) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279719-B2 | Substituted bicyclic pyrimidine-based compounds and compositions and uses thereof | GGPS1, TYMP, FDPS | GGPS1 1/4885FDPS 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.