Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.62 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNG | P07510 | 1/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRND | Q07001 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238711 | 1.00 | CHRNB2 (0.62) | CHRNB2CHRNA4ALDH1A1RECQLCYP3A4 | |
| SCHEMBL4490297 | 0.90 | CHRNB2 (0.61) | CHRNB2CHRNA4CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL29469519 | 0.89 | CHRNB2 (0.56) | CHRNB2CHRNA4ALDH1A1RECQLCYP3A4 | |
| SCHEMBL12568183 | 0.89 | CHRNB2 (0.56) | CHRNB2CHRNA4ALDH1A1RECQLCYP3A4 | |
| SCHEMBL30461625 | 0.84 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL19875367 | 0.84 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA3CHRNA7CHRNA1 | |
| SCHEMBL15429530 | 0.84 | CHRNB2 (0.50) | CHRNB2CHRNA4KMT2A | |
| SCHEMBL3220953 | 0.83 | — | — | |
| SCHEMBL5749788 | 0.83 | CYP19A1 (0.53) | CHRNB2CHRNA4ALDH1A1RECQLCYP3A4 | |
| SCHEMBL5751218 | 0.82 | CYP19A1 (0.73) | ALDH1A1RECQLCYP3A4CYP2D6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12109263-B2 | Integrin agonists or activating compounds and methods for making and using same | 7 HILLS PHARMA INC. | 2024-10-08 | — | — | US | disclosed |
| US-20220118086-A1 | INTEGRIN AGONISTS OR ACTIVATING COMPOUNDS AND METHODS FOR MAKING AND USING SAME | 7 Hills Pharma LLC (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220118086-A1 | INTEGRIN AGONISTS OR ACTIVATING COMPOUNDS AND METHODS FOR MAKING AND USING SAME | ICOS, CD47, CD274 | CHRNB2 535/4885CHRNA4 504/4885ALDH1A1 398/4885 |
| US-12109263-B2 | Integrin agonists or activating compounds and methods for making and using same | ICOS, CD47, CD274 | CHRNB2 535/4885CHRNA4 504/4885ALDH1A1 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.