Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531128 | 1.00 | ALOX15 (1.00) | ALOX15AKR1B1MEN1LMNAMAPT | |
| SCHEMBL21528315 | 0.85 | ALOX15 (0.73) | ALOX15AKR1B1MEN1LMNAMAPT | |
| SCHEMBL30298316 | 0.85 | ALOX15 (0.73) | ALOX15AKR1B1MEN1LMNAMAPT | |
| SCHEMBL29367556 | 0.82 | MAPK1 (1.00) | ALOX15AKR1B1MEN1LMNAMAPT | |
| SCHEMBL899494 | 0.82 | MAPK1 (1.00) | ALOX15AKR1B1MEN1LMNAMAPT | |
| SCHEMBL30298315 | 0.81 | MEN1 (1.00) | ALOX15AKR1B1MEN1LMNAMAPT | |
| SCHEMBL30298313 | 0.81 | MEN1 (1.00) | ALOX15AKR1B1MEN1LMNAMAPT | |
| SCHEMBL30298317 | 0.81 | MEN1 (1.00) | ALOX15AKR1B1MEN1LMNAMAPT | |
| SCHEMBL29469602 | 0.79 | MAPK1 (0.71) | ALOX15AKR1B1MEN1LMNAMAPT | |
| SCHEMBL5527228 | 0.79 | ALOX15 (1.00) | ALOX15AKR1B1MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11908550-B2 | Method for determining different PBDEs derivatives from their response to activities of enoyl-ACP reductase | NANJING UNIVERSITY (CN) | 2024-02-20 | — | — | US | claimed |
| US-20220119850-A1 | Method for determining different PBDEs derivatives from their response to activities of enoyl-ACP reductase | NANJING UNIVERSITY (CN) | 2022-04-21 | — | — | US | claimed |
| US-11908550-B2 | Method for determining different PBDEs derivatives from their response to activities of enoyl-ACP reductase | NANJING UNIVERSITY (CN) | 2024-02-20 | — | — | US | disclosed |
| US-20220119850-A1 | Method for determining different PBDEs derivatives from their response to activities of enoyl-ACP reductase | NANJING UNIVERSITY (CN) | 2022-04-21 | — | — | US | disclosed |